anti-Humain HSPB1 anticorps pour Enzyme Immunoassay

Recommended HSPB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Heat Shock 27kDa Protein 1 (HSPB1) Anticorps
  • CMT2F
  • HMN2B
  • HS.76067
  • HSP27
  • HSP28
  • Hsp25
  • SRP27
  • 27kDa
  • Hsp27
  • cb153
  • cb660
  • hsp1
  • hsp25
  • hsp27
  • id:ibd2821
  • sb:cb660
  • zgc:103437
  • HSPB1
  • cmt2f
  • hs.76067
  • hsp28
  • heat shock protein family B (small) member 1
  • heat shock protein 1
  • heat shock protein, alpha-crystallin-related, 1
  • heat shock protein family B (small) member 1 L homeolog
  • HSPB1
  • Hspb1
  • hspb1
  • hspb1.L
Épitope
AA 1-205, N-Term
84
68
58
44
22
18
18
16
16
13
13
9
7
6
6
5
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
1015
400
374
190
161
104
89
88
84
68
49
44
36
30
13
11
6
4
3
2
2
2
1
1
1
1
Hôte
Souris
562
473
3
Clonalité
Monoclonal
Conjugué
Cet anticorp HSPB1 est non-conjugé
44
40
30
29
24
20
16
13
13
12
10
10
10
10
10
9
9
9
8
8
8
8
8
8
8
8
8
6
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
894
446
307
304
284
269
216
210
76
76
75
58
40
18
13
6
5
4
2
2
1
1
1
Fournisseur
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N° du produit ABIN317528
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN358314 EIA Rabbit Ig Fraction pSer78 Connectez-vous pour afficher Polyclonal 5
1 ABIN453119 EIA WB Rabbit Middle Region Connectez-vous pour afficher Polyclonal 5
1 ABIN400642 EIA IF IHC (p) IP WB Mouse IgG1 Connectez-vous pour afficher n-a 0
1 ABIN265470 EIA IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal 0
1 ABIN5611604 EIA IHC (p) WB Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN1107614 EIA IF IHC (p) WB Mouse IgG1 Connectez-vous pour afficher 5D7 2
1 ABIN5552201 EIA IHC (p) WB Rabbit Ig Fraction Ser78 Connectez-vous pour afficher Polyclonal 0
1 ABIN5552200 EIA WB Rabbit Ig Fraction Ser83 Connectez-vous pour afficher Polyclonal 0
1 ABIN5552202 EIA IHC (p) WB Rabbit Ig Fraction Ser82 Connectez-vous pour afficher Polyclonal 0
1 ABIN5550951 EIA IHC (p) IP WB Mouse IgG2b Connectez-vous pour afficher 5D12-A12 0
1 ABIN5550950 EIA IHC (p) IP WB Mouse IgG2b Connectez-vous pour afficher 5D12-A12 0
1 ABIN613191 EIA RIA Biotin Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN613665 EIA RIA Rabbit IgG Connectez-vous pour afficher Polyclonal 0

General

Antigène Heat Shock 27kDa Protein 1 (HSPB1) Anticorps
Épitope AA 1-205, N-Term
(84), (68), (58), (44), (22), (18), (18), (16), (16), (13), (13), (9), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain
(1015), (400), (374), (190), (161), (104), (89), (88), (84), (68), (49), (44), (36), (30), (13), (11), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Hôte Souris
(562), (473), (3)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp HSPB1 est non-conjugé
(44), (40), (30), (29), (24), (20), (16), (13), (13), (12), (10), (10), (10), (10), (10), (9), (9), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(894), (446), (307), (304), (284), (269), (216), (210), (76), (76), (75), (58), (40), (18), (13), (6), (5), (4), (2), (2), (1), (1), (1)
Pubmed 3 références disponible
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Détail du produit anti-HSPB1 anticorps

Détail du antigène HSPB1 Information d'application Stockage References for anti-HSPB1 antibody (ABIN317528) Images
Specificité The antibody recognizes human Hsp27. Other species not tested.
Attributs du produit Synonyms: Heat shock protein beta-1, Heat shock 27 kDa protein, HSP28, 28 kDa heat shock protein,SRP27, HSP25, Stress-responsive protein 27, Estrogen-regulated 24 kDa protein
Purification Protein-G affinity chromatography
Immunogène Recombinant human Hsp27 (1-205 aa) purified from E. coli
Clone 2A5
Isotype IgG1
Plasmids, Primers & others

Détail du antigène HSPB1

Détail du produit anti-HSPB1 anticorps Information d'application Stockage References for anti-HSPB1 antibody (ABIN317528) Images Haut de la page
Antigène
Autre désignation HSPB1 / HSP27 (HSPB1 Antibody Extrait)
Sujet Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.Synonyms: 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, HSP25, HSP28, Heat shock 27 kDa protein, Heat shock protein beta-1, SRP27, Stress-responsive protein 27
ID gène 3315
UniProt P04792
Pathways Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling

Information d'application

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Stockage References for anti-HSPB1 antibody (ABIN317528) Images Haut de la page
Indications d'application ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Parffin embedded tissue (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application References for anti-HSPB1 antibody (ABIN317528) Images Haut de la page
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Date de péremption 12 months

References for anti-HSPB1 antibody (ABIN317528)

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application Stockage Images Haut de la page
Background publications

Borrelli, Bernock, Landry, Spitz, Weber, Hickey, Freeman, Corry: "Stress protection by a fluorescent Hsp27 chimera that is independent of nuclear translocation or multimeric dissociation." dans: Cell stress & chaperones, Vol. 7, Issue 3, pp. 281-96, 2002

Butt, Immler, Meyer, Kotlyarov, Laass, Gaestel: "Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants." dans: The Journal of biological chemistry, Vol. 276, Issue 10, pp. 7108-13, 2001

Charette, Lavoie, Lambert, Landry: "Inhibition of Daxx-mediated apoptosis by heat shock protein 27." dans: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7602-12, 2000

Images

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application Stockage References for anti-HSPB1 antibody (ABIN317528) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (ABIN317528) anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (ABIN317528) anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (ABIN317528) anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (ABIN317528) anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 1-205), (N-Term) antibody (Image 4)