anti-Humain PDPK1 anticorps pour Intracellular Staining

Recommended PDPK1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Anticorps
  • pdpk1
  • MGC82080
  • PDK1
  • PDPK2
  • PRO0461
  • Pdk1
  • si:zfos-979f1.3
  • 1210
  • BG02759
  • CG1201
  • CG1210
  • DSTPK61
  • Dmel\\CG1210
  • Dstpk61
  • PDK
  • PDK-1
  • PDK1/Pk61C
  • PK61C
  • Pk61C
  • Pk61C/PDK1
  • dPDK-1
  • dPDK1
  • dSTPK61
  • pk61c
  • 3'-phosphoinositide-dependent protein kinase 1
  • 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1
  • ATPDK1
  • AtPDK1
  • T32M21.110
  • T32M21_110
  • 3-phosphoinositide dependent protein kinase 1
  • 3-phosphoinositide dependent protein kinase 1 L homeolog
  • 3-phosphoinositide dependent protein kinase-1
  • 3-phosphoinositide-dependent protein kinase 1
  • pyruvate dehydrogenase kinase, isozyme 1
  • pyruvate dehydrogenase kinase 1
  • Phosphoinositide-dependent kinase 1
  • 3'-phosphoinositide-dependent protein kinase 1
  • PDPK1
  • pdpk1.L
  • pdpk1
  • Pdpk1
  • LOC100380750
  • pdk1
  • PDK1
  • Pdk1
  • pdk-1
Épitope
pSer241
57
35
32
27
27
26
18
17
15
15
15
15
7
7
6
6
6
5
5
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
459
218
217
19
13
12
11
11
6
5
4
3
2
1
1
1
1
1
1
1
Hôte
Souris
380
72
16
Clonalité
Monoclonal
Conjugué
Cet anticorp PDPK1 est conjugé à/à la Alexa Fluor 647
19
17
16
11
10
7
7
7
7
7
7
7
7
7
7
6
5
5
5
4
3
3
3
2
2
1
1
1
1
1
Application
Intracellular Staining (ICS)
312
158
99
91
65
63
40
31
22
10
7
5
2
2
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Request

Recevoir ce produit gratuitement

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

N° du produit ABIN1177137
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1177138 ICS Alexa Fluor 488 Mouse IgG1, kappa pSer241 Connectez-vous pour afficher J66-653-44-17 1
1 ABIN1177136 ICS PE Mouse IgG1, kappa pSer241 Connectez-vous pour afficher J66-653-44-17 1

General

Antigène 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Anticorps
Épitope pSer241
(57), (35), (32), (27), (27), (26), (18), (17), (15), (15), (15), (15), (7), (7), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(459), (218), (217), (19), (13), (12), (11), (11), (6), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Hôte Souris
(380), (72), (16)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp PDPK1 est conjugé à/à la Alexa Fluor 647
(19), (17), (16), (11), (10), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (5), (5), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Application Intracellular Staining (ICS)
(312), (158), (99), (91), (65), (63), (40), (31), (22), (10), (7), (5), (2), (2), (1)
Pubmed 1 référence disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-PDPK1 anticorps

Détail du antigène PDPK1 Information d'application Stockage References for anti-PDPK1 antibody (ABIN1177137) Images
Marque BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène Phosphorylated Human PDPK1 Peptide
Clone J66-653-44-17
Isotype IgG1, kappa

Détail du antigène PDPK1

Détail du produit anti-PDPK1 anticorps Information d'application Stockage References for anti-PDPK1 antibody (ABIN1177137) Images Haut de la page
Antigène
Autre désignation PDPK1 (PDPK1 Antibody Extrait)
Sujet The serine/threonine kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDPK1, also known as PDK1) contributes to the activation of many important kinases in the insulin and IGF-1 signaling pathways. It acts downstream of phosphatidylinositol 3-kinase (PI3-kinase) to phosphorylate residues in the activation loops of many cellular kinases, including protein kinase B (PKB/Akt), PKC isoforms, p70 S6 kinase, and PDPK1 itself. The autophosphorylation of PDPK1 at serine 241 (S241) has recently been suggested to play a role in the regulation of PDPK1. It has been proposed that PDPK1 activity plays a key role in the regulation of various cellular events such as cell proliferation, differentiation, and apoptosis. The J666-653.44.17 monoclonal antibody recognizes the phosphorylated S241 in the activation loop of human PDPK1. The orthologous phosphorylation site in mouse and rat PDPK1 is S244.
Synonyms: PDK1 (pS241), PKB Kinase (pS241)
Domaine de recherche Kinases/Phosphatases
Pathways Signalisation PI3K-Akt, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals

Information d'application

Détail du produit anti-PDPK1 anticorps Détail du antigène PDPK1 Stockage References for anti-PDPK1 antibody (ABIN1177137) Images Haut de la page
Volume d'échantillon 20 μL
Restrictions For Research Use only

Stockage

Détail du produit anti-PDPK1 anticorps Détail du antigène PDPK1 Information d'application References for anti-PDPK1 antibody (ABIN1177137) Images Haut de la page
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References for anti-PDPK1 antibody (ABIN1177137)

Détail du produit anti-PDPK1 anticorps Détail du antigène PDPK1 Information d'application Stockage Images Haut de la page
Produit citée dans:

Wick, Ramos, Chen, Quon, Dong, Liu: "Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop." dans: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 42913-9, 2003