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anti-Human PIP5K1B Anticorps:
anti-Mouse (Murine) PIP5K1B Anticorps:
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Human Polyclonal PIP5K1B Primary Antibody pour IHC (p), WB - ABIN392594
Qin, Li, Pan, Wu: Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. dans The Journal of biological chemistry 2009
Show all 2 Pubmed References
Human Polyclonal PIP5K1B Primary Antibody pour ELISA, WB - ABIN521867
Bayot, Reichman, Lebon, Csaba, Aubry, Sterkers, Husson, Rak, Rustin: Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies. dans Human molecular genetics 2013
Data indicate that type I phosphatidylinositol 4-phosphate 5-kinase (Montrer PIP4K2C Anticorps) PIP5KIbeta mutants whose dimerization was impaired showed a severe decrease in PI(4,5)P2 production and plasma membrane delocalization.
Knockdown of PIP5K1B in fibroblasts reproduced abnormal actin cytoskeleton remodeling evidenced in Friedreich's ataxia patient cells.
Results identify an isoform-specific PDZ (Montrer INADL Anticorps)-binding motif in PIP5KIbeta, which confers specificity for PIP5KIbeta signaling at the uropod during leukocyte chemotaxis.
findings show that the human type I phosphatidylinositol 4-phosphate 5-kinase (Montrer PIP4K2C Anticorps) isoform beta (PIPKIbeta) has a role in organizing signaling at the cell rear
Syk (Montrer SYK Anticorps)-dependent phosphorylation of PIP5K1B is the dominant modification responsible for the decrease in cellular phosphatidylinositol 4,5-bisphosphate.
synthesis of PtdIns(4,5)P(2) mediated by PIP5KIbeta is rate limiting for apical but not basolateral endocytosis in polarized kidney cells
The results suggested that PIP5K1A and PIP5K1B may coordinately and/or redundantly function in the maintenance of sperm number and morphology during spermatogenesis.
Phosphatidylinositol 4-phosphate 5-kinase (Montrer PIP4K2C Anticorps) is essential for ROCK-mediated neurite remodeling
PIPKIalpha activity is involved in the actin remodeling that is a prerequisite for efficient phagocytosis
These results indicate that both Arf6 (Montrer ARF6 Anticorps) and PIP5K (Montrer PIKFYVE Anticorps) are involved in integrin-dependent bacterial uptake, and that Arf6 (Montrer ARF6 Anticorps) participates in both activation of PIP5K (Montrer PIKFYVE Anticorps) as well as in other events associated with bacterial uptake.
findings indicate that synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) by the three phosphatidylinositol 4-phosphate 5-kinase (Montrer PIP4K2C Anticorps) (PIP5K (Montrer PIKFYVE Anticorps)) isoforms Ialpha, Ibeta and Igamma is controlled by Rho GTPases
phosphatidylinositol phosphate kinase type I alpha is a negative regulator of FcepsilonRI (Montrer FCER1A Anticorps)-mediated cellular responses and anaphylaxis.
after stimulation of a G protein-coupled receptor (Montrer GPR34 Anticorps), IP(3) is completely derived from a rapidly synthesized discrete pool of PIP(2) synthesized by PIP5KIalpha and PIP5KIbeta
Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity).
, phosphatidylinositol 4-phosphate 5-kinase type I beta
, phosphatidylinositol 4-phosphate 5-kinase type-1 beta
, phosphatidylinositol-4-phosphate 5-kinase type-1 beta
, protein STM-7
, ptdIns(4)P-5-kinase 1 beta
, type I phosphatidylinositol 4-phosphate 5-kinase beta
, type I phosphatidylinositol-4-phosphate 5-kinase beta
, phosphatidylinositol 4-phosphate 5-kinase type I alpha
, phosphatidylinositol-4-phosphate 5-kinase type I alpha
, phosphatidylinositol-4-phosphate 5-kinase type I beta
, phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
, phosphatidylinositol-4-phosphate 5-kinase, type 1, beta
, ptdIns(4)P-5-kinase beta
, phosphatidylinositol-4-phosphate 5-kinase, type I, beta
, phosphatidylinositol-4-phosphate 5-kinase type-1 beta-like