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Envoyez-nous votre proposition de validation. J'aimerais valider ce produitRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Fournisseur | Clonality | References | Details |
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1 | ABIN954275 | EIA IHC (p) IP WB | Mouse | IgG2a | Connectez-vous pour afficher | 1F3 | 0 |
General |
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Antigène | Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) Anticorps |
Épitope | AA 110-139 Alternatives |
Reactivité | Humain Alternatives |
Hôte | Lapin Alternatives |
Clonalité | |
Conjugué | Cet anticorp PPP2R2B est non-conjugé Alternatives |
Application |
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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3 références disponible |
Fournisseur | Connectez-vous pour afficher |
Détail du produit anti-PPP2R2B anticorpsDétail du antigène PPP2R2B Information d'application Stockage References for anti-PPP2R2B antibody (ABIN453788) Images |
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Specificité | This antibody recognizes PPP2R2B. |
Réactivité croisée (Details) | Species reactivity (tested):Human. |
Purification | Protein A Chromatography followed by peptide Affinity purification. |
Immunogène | KLH conjugated synthetic peptide between 110~139 amino acids from the Center region of Human PPP2R2B. Genename: PPP2R2B |
Détail du antigène PPP2R2BDétail du produit anti-PPP2R2B anticorps Information d'application Stockage References for anti-PPP2R2B antibody (ABIN453788) Images Haut de la page |
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Antigène | |
Autre désignation | PPP2R2B (PPP2R2B Antibody Extrait) |
Sujet | PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.Synonyms: B55-beta isoform, PP2A subunit B B-beta isoform, PR55-beta isoform, R2-beta isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta |
Poids moléculaire | 51710 Da |
ID gène | 5521 |
NCBI Accession | NP_001120853 |
UniProt | Q00005 |
Pathways | Signalisation PI3K-Akt, Mitotic G1-G1/S Phases, Hepatitis C |
Information d'applicationDétail du produit anti-PPP2R2B anticorps Détail du antigène PPP2R2B Stockage References for anti-PPP2R2B antibody (ABIN453788) Images Haut de la page |
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Indications d'application |
ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/10-1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
Restrictions | For Research Use only |
StockageDétail du produit anti-PPP2R2B anticorps Détail du antigène PPP2R2B Information d'application References for anti-PPP2R2B antibody (ABIN453788) Images Haut de la page |
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Format | Liquid |
Concentration | 0.25 mg/mL |
Buffer | PBS with 0.09 % (W/V) Sodium Azide as preservative. |
Agent conservateur | Sodium azide |
Précaution d'utilisation | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Conseil sur la manipulation | Avoid repeated freezing and thawing. |
Stock | 4 °C/-20 °C |
Stockage commentaire | Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. |
References for anti-PPP2R2B antibody (ABIN453788)Détail du produit anti-PPP2R2B anticorps Détail du antigène PPP2R2B Information d'application Stockage Images Haut de la page |
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Background publications |
Rajkiewicz, Sułek-Piatkowska, Krysa, Zdzienicka, Szirkowiec, Zaremba: "Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia." dans: Neurologia i neurochirurgia polska, Vol. 42, Issue 6, pp. 497-504, 2009 Ben-Israel, Sharf, Rechavi, Kleinberger: "Adenovirus E4orf4 protein downregulates MYC expression through interaction with the PP2A-B55 subunit." dans: Journal of virology, Vol. 82, Issue 19, pp. 9381-8, 2008 Strack, Zaucha, Ebner, Colbran, Wadzinski: "Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits." dans: The Journal of comparative neurology, Vol. 392, Issue 4, pp. 515-27, 1998 |
ImagesDétail du produit anti-PPP2R2B anticorps Détail du antigène PPP2R2B Information d'application Stockage References for anti-PPP2R2B antibody (ABIN453788) Haut de la page |
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Supplier Images |
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