anti-Humain TEK anticorps pour Enzyme Immunoassay

Recommended TEK Antibody

Antigène
TEK Tyrosine Kinase, Endothelial (TEK) Anticorps
  • TEK
  • DKFZp469E064
  • AA517024
  • Cd202b
  • Hyk
  • Tie2
  • tie-2
  • CD202B
  • TIE-2
  • TIE2
  • VMCM
  • VMCM1
  • Tie-2
  • tie2
  • TEK receptor tyrosine kinase
  • angiopoietin-1 receptor
  • TEK tyrosine kinase, endothelial
  • TEK
  • LOC100408334
  • tek
  • Tek
Épitope
pTyr1113
29
25
22
20
15
15
11
10
10
8
8
8
6
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
288
164
101
9
8
Hôte
Lapin
236
64
10
3
2
1
Clonalité
Polyclonal
Conjugué
Cet anticorp TEK est non-conjugé
21
14
10
8
8
8
8
8
8
7
6
4
4
4
4
4
4
1
Application
Enzyme Immunoassay (EIA)
174
128
69
53
48
22
21
19
16
12
7
6
6
3
Options

Images

N° du produit ABIN358489
$ 484.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN155164 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Cl-9 3
1 ABIN155163 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Cl-2 3
1 ABIN155165 EIA FACS WB Biotin Mouse IgG1 Cl-16 4
1 ABIN115157 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Cl-9 4
1 ABIN115155 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Cl-2 4
1 ABIN115159 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Cl-16 4
1 ABIN5552253 EIA IHC (p) WB Rabbit Ig Fraction C-Term Polyclonal 0

General

Antigène TEK Tyrosine Kinase, Endothelial (TEK) Anticorps
Épitope pTyr1113
(29), (25), (22), (20), (15), (15), (11), (10), (10), (8), (8), (8), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain
(288), (164), (101), (9), (8)
Hôte Lapin
(236), (64), (10), (3), (2), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp TEK est non-conjugé
(21), (14), (10), (8), (8), (8), (8), (8), (8), (7), (6), (4), (4), (4), (4), (4), (4), (1)
Application Enzyme Immunoassay (EIA)
(174), (128), (69), (53), (48), (22), (21), (19), (16), (12), (7), (6), (6), (3)
Pubmed 5 références disponible
Fournisseur

Détail du produit anti-TEK anticorps

Détail du antigène TEK Information d'application Stockage References for anti-TEK antibody (ABIN358489) Images
Specificité This antibody detects TEK pTyr1113. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
Purification Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Immunogène This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.
Isotype Ig Fraction
Plasmids, Primers & others

Détail du antigène TEK

Détail du produit anti-TEK anticorps Information d'application Stockage References for anti-TEK antibody (ABIN358489) Images Haut de la page
Antigène
Autre désignation CD202b / TEK (TEK Antibody Extrait)
Sujet The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
Poids moléculaire 125810 Da
ID gène 83659, 9606
UniProt Q02763
Pathways Signalisation RTK, Growth Factor Binding

Information d'application

Détail du produit anti-TEK anticorps Détail du antigène TEK Stockage References for anti-TEK antibody (ABIN358489) Images Haut de la page
Indications d'application ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-TEK anticorps Détail du antigène TEK Information d'application References for anti-TEK antibody (ABIN358489) Images Haut de la page
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-TEK antibody (ABIN358489)

Détail du produit anti-TEK anticorps Détail du antigène TEK Information d'application Stockage Images Haut de la page
Background publications

Cascone, Audero, Giraudo, Napione, Maniero, Philips, Collard, Serini, Bussolino: "Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1." dans: Blood, Vol. 102, Issue 7, pp. 2482-90, 2003

DeBusk, Chen, Nishishita, Chen, Thomas, Lin: "Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis." dans: Arthritis and rheumatism, Vol. 48, Issue 9, pp. 2461-71, 2003

Poncet, Gasc, Janzer, Meyer, Juillerat-Jeanneret: "Expression of Tie-2 in human peripheral and autonomic nervous system." dans: Neuropathology and applied neurobiology, Vol. 29, Issue 4, pp. 361-9, 2003

Lee, Koh: "Shear stress activates Tie2 receptor tyrosine kinase in human endothelial cells." dans: Biochemical and biophysical research communications, Vol. 304, Issue 2, pp. 399-404, 2003

Sussman, Upalakalin, Roberts, Kocher, Benjamin: "Blood markers for vasculogenesis increase with tumor progression in patients with breast carcinoma." dans: Cancer biology & therapy, Vol. 2, Issue 3, pp. 255-6, 2003

Images

Détail du produit anti-TEK anticorps Détail du antigène TEK Information d'application Stockage References for anti-TEK antibody (ABIN358489) Haut de la page
Images (Fournisseur)
 image for anti-TEK Tyrosine Kinase, Endothelial (TEK) (pTyr1113) antibody (ABIN358489) anti-TEK Tyrosine Kinase, Endothelial (TEK) (pTyr1113) antibody