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anti-Human TAB3 Anticorps:
anti-Mouse (Murine) TAB3 Anticorps:
anti-Rat (Rattus) TAB3 Anticorps:
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The combination of WES, genomic triangulation, and systems biology has uncovered perturbations in TGF-beta activated kinase 1 (Montrer MAP3K7 Anticorps) signaling as a novel pathogenic substrate for polyvalvular syndrome.
Our study provides insights into the mechanism of TAB3 regulating activity and suggests its important implications in triple negative breast cancer metastasis.
Data show that knockdown of transforming growth factor-activated kinase 1 (TAK1)-binding protein 3 (TAB3) inhibited proliferation of non-small cell lung cancer (NSCLC) cells.
TAB3 regulated ovarian cancer cell bioactivity and chemotherapy performance via the NF-kappaB (Montrer NFKB1 Anticorps) pathway.
Upregulation of miR (Montrer MLXIP Anticorps)-532-5p and subsequent suppression of the SESTD1 (Montrer SESTD1 Anticorps) and TAB3 genes represent an antiviral response aimed at limiting West Nile virus infection.
miR (Montrer MLXIP Anticorps)-30a in MSCs may participate in the immune dysregulation of the maternal-fetal interface during PE
miR (Montrer MLXIP Anticorps)-26b suppresses NF-kappaB (Montrer NFKB1 Anticorps) signaling and sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis by inhibiting the expression of TAK1 (Montrer MAP3K7 Anticorps) and TAB3.
conclude that TRIM38 (Montrer TRIM38 Anticorps) negatively regulates TNFalpha (Montrer TNF Anticorps)- and IL-1beta (Montrer IL1B Anticorps)-induced signaling by mediating lysosome-dependent degradation of TAB2 (Montrer TAB2 Anticorps)/3, two critical components in TNFalpha (Montrer TNF Anticorps)- and IL-1beta (Montrer IL1B Anticorps)-induced signaling pathways
Studies show that three proteins expressed in HEK (Montrer EPHA3 Anticorps)-293T cells (NAP1 (Montrer IL8 Anticorps), TANK and TBKBP1 (Montrer TBKBP1 Anticorps)) interact with TBK1 (Montrer TBK1 Anticorps).
MiR (Montrer MLXIP Anticorps)-23b suppresses IL-17 (Montrer IL17A Anticorps)-, tumor necrosis factor alpha (TNF-alpha (Montrer TNF Anticorps))- or IL-1beta (Montrer IL1B Anticorps)-induced NF-kappaB (Montrer NFKB1 Anticorps) activation and inflammatory cytokine expression by targeting TAB2 (Montrer TAB2 Anticorps), TAB3 and IKK-alpha (Montrer CHUK Anticorps).
Findings indicate that the absence of TAB3 plays a harmful role in ischemic heart disease
TAB2 (Montrer TAB2 Anticorps) and TAB3 are essential for B cell activation (Montrer BLNK Anticorps) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
NF-kappa-B-activating protein 1
, NFkB activating protein 1
, TAK1-binding protein 3
, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
, TGF-beta-activated kinase 1-binding protein 3
, mitogen-activated protein kinase kinase kinase 7 interacting protein 3
, mitogen activated protein kinase kinase kinase 7 interacting protein 3
, mitogen-activated protein kinase kinase kinase 7-interacting protein 3
, TGF-beta activated kinase 1/MAP3K7 binding protein 3
, mitogen-activated protein kinase kinase kinase 7-interacting protein 3-like
, TAK-1 binding protein, hypothetical protein Zn finger
, mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like
, LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 3