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anti-Human TNFAIP3 Anticorps:
anti-Mouse (Murine) TNFAIP3 Anticorps:
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Human Monoclonal TNFAIP3 Primary Antibody pour CyTOF, FACS - ABIN4277015
Kupfner, Arcaroli, Yum, Nadler, Yang, Abraham: Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis. dans Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 38 Pubmed References
TNFAIP3 abnormality was less prevalent among intestinal diffuse large B-cell lymphomas with some discordancy between gene deletion and protein expression.
antidepressant treatment exerts anti-inflammatory effects, at least in part through increased expression of the TNFAIP3 gene
A20 regulates canonical wnt (Montrer WNT2 Anticorps)-signaling through an interaction with RIPK4 (Montrer RIPK4 Anticorps)
these results suggested that in human colorectal cancer cells, A20 may function to inhibit cancer progression via down-regulation of TNFalpha (Montrer TNF Anticorps)-induced chemokine (Montrer CCL1 Anticorps) production by suppression of ERK (Montrer EPHB2 Anticorps) signaling
A20 was significantly downregulated while p-p65 (RelA (Montrer NFkBP65 Anticorps)) significantly upregulated in the radioresistant nasopharyngeal carcinoma (NPC (Montrer NPC1 Anticorps))relative to radiosensitive NPCs, and miR (Montrer MLXIP Anticorps)-125b expression level was negatively associated with A20 expression level, whereas positively associated with p-p65 (RelA (Montrer NFkBP65 Anticorps)) level
Low A20 expression is associated with HIV disease.
Gene polymorphisms of TNF (Montrer TNF Anticorps)-238G/A, TNF (Montrer TNF Anticorps)-308G/A, IL10 (Montrer IL10 Anticorps)-1082G/A, TNFAIP3, and MC4R (Montrer MC4R Anticorps) and comorbidity occurrence in a Romanian population with psoriasis
A20 overexpression in vivo significantly reduced renal injury as demonstrated by the improved levels of Scr and BUN and the reduction in histological damage.
the risk allele for the TNFAIP3 rs2230926 polymorphism was associated with systemic lupus erythematosus susceptibility.
It was concluded that the A20 protein in macrophages modulates lung injury induced by LPS (Montrer IRF6 Anticorps). The overexpression of A20 in macrophages may be involved in modulating macrophage polarization.
T cell-specific A20 limited the expansion but reduced apoptosis and necroptosis of Listeria-specific CD8 (Montrer CD8A Anticorps)(+) T cells, resulting in an impaired pathogen control in primary but improved clearance in secondary infection.
study reveals a critical role of IL-17RC (Montrer IL17RC Anticorps) in maintaining baseline A20 production and a novel role of the IL-17RC (Montrer IL17RC Anticorps)-A20 axis in controlling JNK (Montrer MAPK8 Anticorps) isoform-dependent tumor-specific homeostatic proliferation.
The data demonstrate that miR (Montrer MLXIP Anticorps)-125b regulates nasopharyngeal carcinoma cell proliferation and apoptosis by targeting A20/NF-kappaB (Montrer NFKB1 Anticorps) signaling pathway, and miR (Montrer MLXIP Anticorps)-125b acts as oncogene (Montrer RAB1A Anticorps), whereas A20 functions as tumor suppressor.
Mice with A20 deficient B cells are prone to food allergy.
Tnfaip3, an anti-inflammatory gene, is located precisely underneath the linkage peak and contains two non-synonymous SNPs leading to conservative amino acid substitutions.
Hepatitis C virus core protein ligates gC1qR (Montrer C1QBP Anticorps) to induce A20 expression in macrophages via P38 (Montrer CRK Anticorps), JNK (Montrer MAPK8 Anticorps) and NF-kappaB (Montrer NFKB1 Anticorps) signaling pathways, which leads to a low-grade chronic inflammation during HCV infection.
These results suggest that Leishmania exploits A20 and UCP2 (Montrer UCP2 Anticorps) to impair inflammasome activation for disease propagation
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1 (Montrer SNAI1 Anticorps).
holding thymic production of natural Treg cells in check, A20 integrates Treg cell activity and increased effector T cell survival into an efficient CD4 (Montrer CD4 Anticorps)(+) T cell response
these studies establish A20 as a crucial hepatoprotective factor.
Data show the characterization and deduced amino acid sequence analysis for A20 gene which expression increases in MDBK cells infected by BVDV-1. Also, regulatory regions for NF-kappaB (Montrer NFKB1 Anticorps) and Sp-1 (Montrer SP1 Anticorps) additionally to an ARE element for mRNA stability were detected
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
tumor necrosis factor, alpha-induced protein 3
, OTU domain-containing protein 7C
, TNF alpha-induced protein 3
, putative DNA-binding protein A20
, tumor necrosis factor alpha-induced protein 3
, tumor necrosis factor inducible protein A20
, zinc finger protein A20
, tumor necrosis factor induced protein 3