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APAF1 anticorps (AA 12-28)
APAF1
Reactivité: Humain, Souris
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-APAF1 anticorps
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Antigène
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APAF1
(Apoptotic Peptidase Activating Factor 1 (APAF1))
Épitope
Tous les épitopes à travers APAF1 Anticorps.
AA 12-28
Reactivité
Toutes les réactivités sur APAF1 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur APAF1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur APAF1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers APAF1 Anticorps
Cet anticorp APAF1 est non-conjugé
Application
Tous les applications à travers APAF1 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody recognises a 130 kDa band in Western blots.
Purification
Afinity Chromatography
Immunogène
Synthetic peptide corresponding to amino acids 12-28 of Human Apaf1
Isotype
IgG
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Information d'application
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Indications d'application
Western Blot: 1/1000 - 1/2000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
PBS, 0.02 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur APAF1
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Antigène
APAF1
(Apoptotic Peptidase Activating Factor 1 (APAF1))
Autre désignation
APAF1 (APAF1 Produits )
Synonymes
anticorps APAF1, anticorps ARK, anticorps Apaf-1, anticorps Apaf1, anticorps CG6829, anticorps D-Apaf-1, anticorps DARK, anticorps Dapaf-1, anticorps Dapaf-1/HAC-1, anticorps Dark, anticorps Dark/Apaf-I, anticorps Dark/Dapaf-1/HAC1, anticorps Dark/Hac-1/dApaf-1, anticorps Dark/Hac-1/dApaf1, anticorps Dmel\\CG6829, anticorps Hac-1, anticorps Hac-1/Dark, anticorps Hac1, anticorps T1, anticorps anon-53Fa, anticorps apaf-1, anticorps apaf1, anticorps arc, anticorps ark, anticorps dAPAF-1, anticorps dApaf-1, anticorps dApaf-1/DARK/HAC-1, anticorps dApaf1, anticorps dArk, anticorps dapaf, anticorps dapaf-1, anticorps dapaf-1L, anticorps dapaf-1S, anticorps dark, anticorps dark/dapaf-1/hac-1, anticorps dark/hac-1/dapaf-1, anticorps hac-1, anticorps hac1, anticorps l(2)SH0173, anticorps APAF-1, anticorps CED4, anticorps 6230400I06Rik, anticorps Apaf1l, anticorps fog, anticorps mKIAA0413, anticorps zgc:136543, anticorps Death-associated APAF1-related killer, anticorps apoptotic peptidase activating factor 1 L homeolog, anticorps apoptotic peptidase activating factor 1, anticorps Dark, anticorps apaf1.L, anticorps apaf1, anticorps APAF1, anticorps Apaf1
Sujet
Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8.Synonyms: Apaf-1, Apoptotic protease-activating factor 1, KIAA0413
ID gène
317
NCBI Accession
NP_001151
UniProt
O14727
Pathways
Signalisation p53 , Apoptose , Caspase Cascade in Apoptosis , Tube Formation , Positive Regulation of Endopeptidase Activity
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