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anti-Human CYP3A4 Anticorps:
anti-Rat (Rattus) CYP3A4 Anticorps:
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Human Polyclonal CYP3A4 Primary Antibody pour IHC (p), WB - ABIN514838
Yamashita, Honda, Nio, Nakamoto, Yamashita, Takamura, Tani, Zen, Kaneko: Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation. dans Cancer research 2010
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Human Monoclonal CYP3A4 Primary Antibody pour ICC, FACS - ABIN969512
van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. dans Drug metabolism and disposition: the biological fate of chemicals 2009
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Human Polyclonal CYP3A4 Primary Antibody pour Func, WB - ABIN2473177
Chirkov YuYu, Tyshchuk, Severina: Guanylate cyclase in human platelets with different aggregability. dans Experientia 1990
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Human Polyclonal CYP3A4 Primary Antibody pour ELISA - ABIN4302113
Choi, Skipper, Wishnok, Tannenbaum: Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450. dans Drug metabolism and disposition: the biological fate of chemicals 2005
Human Polyclonal CYP3A4 Primary Antibody pour WB - ABIN514839
De Bock, Colin, Boussery, Van Bocxlaer: Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes. dans Talanta 2012
Human Polyclonal CYP3A4 Primary Antibody pour IP, WB - ABIN947776
Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. dans Pharmacology research & perspectives 2014
Cow (Bovine) Polyclonal CYP3A4 Primary Antibody pour WB - ABIN2784528
Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. dans Clinical pharmacology and therapeutics 2014
It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (Montrer POR Anticorps) and cytochrome b(5 (Montrer CYB5A Anticorps)).
The alleles CYP3A5 (Montrer CYP3A5 Anticorps)*3 and CYP3A4*18B were significantly associated with dose-adjusted tacrolimus blood trough concentrations and had a strong time-genotype interaction with tacrolimus pharmacokinetics.
The CYP3A4*22 variant allele is significantly associated with lower metabolic ratio of carbamazepine
there is a significant relationship between endogenous CYP3A4 biomarker and in vivo metabolism of cyclosporine in renal transplant recipients
The DEGs (Montrer DEGS1 Anticorps), such as AGTR1 (Montrer AGTR1 Anticorps), CYP3A4 and CYP4A11 (Montrer CYP4A11 Anticorps) may play critical roles in the development of HTN likely via the regulation by hsa (Montrer CD24 Anticorps)-miR (Montrer MLXIP Anticorps)-26b-5p and taking part in some pathways.
The results demonstrated the important role of the CYP (Montrer PPIG Anticorps) 3A4*1B allelic variant as risk factor for developing resistance to antiepileptic drugs in pediatric patients with epilepsy
The established method provides a sensitive tool to evaluate the CYP3A4 protein in human liver homogenates from patients with normal or chronic/severe hepatic injury.
None of the patients with Regorafenib-induced severe toxic hepatitis had CYP3A4 gene mutations. Similar polymorphisms in UGT1A9 (Montrer UGT1A9 Anticorps) gene promoter region were found in both patients who presented acute hepatitis.
We sought to determine the relation between 17-alpha hydroxyprogesterone caproate plasma concentrations, progesterone receptor (Montrer PGR Anticorps) single nucleotide polymorphisms and single nucleotide polymorphisms in CYP3A4 and CYP3A5 (Montrer CYP3A5 Anticorps) and spontaneous preterm birth.
homozygous AA carriers of the CYP3A4 gene respond better to treatment with transdermal buprenorphine for critical limb ischemia
Data suggest that metabolism (and possibly pharmacokinetics) of hypnotic nitrazepam involves liver enzymes AOX1 (aldehyde oxidase 1 (Montrer AOX1 Anticorps)), NAT2 (N-acetyltransferase 2 (Montrer NAT2 Anticorps)), AADAC (arylacetamide deacetylase (Montrer AADAC Anticorps)), and CYP3A4 (cytochrome P450 3A4).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
cytochrome P450 3A4
, cytochrome P450, family 3, subfamily A, polypeptide 4
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4
, Cytochrome P450 CM3A-10
, cytochrome P450 3A21
, 1,8-cineole 2-exo-monooxygenase
, P450-III, steroid inducible
, albendazole monooxygenase
, albendazole sulfoxidase
, cytochrome P450 3A3
, cytochrome P450 HLp
, cytochrome P450 NF-25
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3
, cytochrome P450-PCN1
, glucocorticoid-inducible P450
, nifedipine oxidase
, quinine 3-monooxygenase
, taurochenodeoxycholate 6-alpha-hydroxylase
, cytochrome P450 CYP3A12
, cytochrome P450 3A80