Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL) Kits ELISA

Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. De plus, nous expédions ASTL Anticorps (12) et ASTL Protéines (3) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ASTL 431705 Q6HA08
Anti-Souris ASTL ASTL 215095 Q6HA09
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.06 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$736.84
Détails

Plus Kits ELISA pour ASTL partenaires d'interaction

Human Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL) interaction partners

  1. The SAS1B metalloproteinase is proposed as a prototype cancer-oocyte tumor surface neoantigen for development of targeted immunotherapeutics with limited on-target/off tumor effects predicted to be restricted to the population of growing oocytes.

  2. SAS1B protein [ovastacin] shows temporal and spatial restriction to oocytes in several eutherian orders and initiates translation at the primary to secondary follicle transition.

Mouse (Murine) Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL) interaction partners

  1. Intracellular activation of Astl mediates pre-fertilization hardening of the zona pellucida.

  2. Seven amino acid motif near Astl N-terminus is necessary and sufficient for cortical granule localization.

  3. ASTL is dynamically expressed in the embryonic epithelium and in embryonic stem cells, suggesting an important function for the control of epithelial cell behavior during early development.

  4. Ovastacin is a pioneer component of mouse cortical granules and plays a definitive role in the postfertilization block to sperm binding that ensures monospermic fertilization and successful development

  5. Data show that SAS1B/SAS1R (Sperm Acrosomal SLLP1 Binding/Sperm Acrosomal SLLP1 receptor) bound to sperm acrosomal protein SlLP1 with high affinity.

ASTL profil antigène

Antigen Summary

Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).

Gene names and symbols associated with ASTL

  • astacin like metalloendopeptidase (ASTL) anticorps
  • astacin-like metalloendopeptidase (M12 family) (Astl) anticorps
  • 7420700F21 anticorps
  • C87576 anticorps
  • Sas1b anticorps

Protein level used designations for ASTL

astacin-like metalloendopeptidase , astacin-like metalloendopeptidase (M12 family) , oocyte astacin , ovastacin , sperm acrosomal SLLP1 , sperm acrosomal SLLP1-binding protein

GENE ID SPECIES
431705 Homo sapiens
215095 Mus musculus
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