anti-CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) Anticorps

CTDSP1 encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. De plus, nous expédions CTDSP1 Protéines (7) et CTDSP1 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CTDSP1 363249  
CTDSP1 58190 Q9GZU7
CTDSP1 227292 P58466
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Top anti-CTDSP1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 105 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-CTDSP1 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell CTDSP1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Chèvre Inconjugué ELISA, IHC   100 μg 6 to 7 Days
$429.87
Détails
Humain Chèvre Inconjugué ELISA, IHC, WB   100 μg 6 to 7 Days
$429.87
Détails
Humain Lapin Inconjugué IP, IHC, WB Immunohistochemical analysis of CTDSP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CTDSP1 expression in Jurkat (A), HuvEc (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Souris Chèvre Inconjugué ELISA, WB 0.1 mg 2 to 3 Days
$550.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of CTDSP1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the CTDSP1 antibody detected the CTDSP1 protein (arrow). 0.4 mL 6 to 8 Days
$522.50
Détails
Humain Chèvre Biotin ELISA, IHC, WB   100 μg 6 to 7 Days
$429.87
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HeLa/HuvEc cells, using CTDSP1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$324.50
Détails

anti-CTDSP1 Anticorps mieux référencés

  1. Human Polyclonal CTDSP1 Primary Antibody pour IHC (p), ELISA - ABIN545075 : Yeo, Lin, Dahmus, Gill: A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 Pubmed References

  2. Dog (Canine) Polyclonal CTDSP1 Primary Antibody pour ELISA - ABIN547899 : Zhang, Kim, Genoud, Gao, Kelly, Pfaff, Gill, Dixon, Noel: Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. dans Molecular cell 2006 (PubMed)

Plus d’anticorps contre CTDSP1 partenaires d’interaction

Human CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) interaction partners

  1. REST is a bona fide substrate for SCP1 in vivo and that SCP1 phosphatase activity protects REST against degradation.

  2. Our results provide a novel mechanistic insight into the activation of Myc by 27-HC via transcriptional repression of PP2A, SCP1 and FBW7 to increase Myc protein stability in breast cancer cells.

  3. SCP1 is the phosphatase that counterregulates the MAPK-mediated phosphorylation of Ser(68)-Twist1.

  4. SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Serine-62.

  5. hSCP1 may be an beta-O-linked N-acetylglucosamine modified protein in vivo.

  6. CTDSP1 activity stabilizes REST in stem cells and ERK-dependent phosphorylation combined with Pin1 activity promotes REST degradation in neural progenitors.

  7. SCP1 phosphatase substrate specificity: CdcA3 could be an enzymatic substrate for SCP1.

  8. Captured the phosphoryl-aspartate intermediate in the crystal structure of a Scp1D206A mutant soaked with para-nitrophenyl phosphate (pNPP), providing strong evidence for the proposed mechanism.

  9. Polymorphisms vary significantly between races; Not associated with TB susceptibility in Caucasians.

  10. SCP1 may play a role in the regulation of gene expression, possibly by controlling the transition from initiation/capping to processive transcript elongation

  11. results show that REST/NRSF recruits SCPs to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells

  12. SCP1 acts as a phosphatase for regulatory phosphorylations in the linker region of Smad1 and Smad2.

Mouse (Murine) CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) interaction partners

  1. Consistently, the authors observed increased AKT phosphorylation and angiogenesis followed by enhanced tumorigenesis in Ctdsp1 (which encodes SCP1) gene - knockout mice. Importantly, they discovered that the membrane localization of SCP1 is crucial for impeding angiogenesis and tumor growth, and this localization depends on palmitoylation of a conserved cysteine motif within its NH2 terminus.

  2. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  3. Findings suggest that SCP1 may inhibit the osteoblastic differentiation induced by the BMP-Smad axis via Runx2 by suppressing downstream effector(s).

  4. Expression and purification of the active variant of recombinant murine Golli-interacting protein (GIP) and its characterization

CTDSP1 profil antigène

Profil protéine

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CTDSP1

  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1) anticorps
  • CTD small phosphatase 1 (CTDSP1) anticorps
  • CTD small phosphatase 1 (Ctdsp1) anticorps
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (ctdsp1) anticorps
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (HCAG_04820) anticorps
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTRG_06220) anticorps
  • CTD small phosphatase 1 (ctdsp1) anticorps
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1) anticorps
  • CTDSP1 anticorps
  • fj83f12 anticorps
  • GIP anticorps
  • im:7141428 anticorps
  • Nif3 anticorps
  • NLI-IF anticorps
  • NLIIF anticorps
  • SCP1 anticorps
  • wu:fj83f12 anticorps
  • zgc:113169 anticorps

Protein level used designations for CTDSP1

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 , CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 , NLI-interacting factor 3 , nuclear LIM interactor-interacting factor 3 , small C-terminal domain phosphatase 1 , golli-interacting protein , small CTD phosphatase 1

GENE ID SPECIES
608466 Canis lupus familiaris
516199 Bos taurus
459943 Pan troglodytes
363249 Rattus norvegicus
58190 Homo sapiens
553744 Danio rerio
5447218 Ajellomyces capsulatus NAm1
8301559 Candida tropicalis MYA-3404
100350904 Oryctolagus cuniculus
100380164 Xenopus (Silurana) tropicalis
227292 Mus musculus
100726065 Cavia porcellus
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