Cartilage Acidic Protein 1 (CRTAC1) Kits ELISA

CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. De plus, nous expédions Cartilage Acidic Protein 1 Anticorps (54) et Cartilage Acidic Protein 1 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CRTAC1 55118 Q9NQ79
CRTAC1 72832 Q8R555
Anti-Rat CRTAC1 CRTAC1 171438  
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 1.17 ng/mL 4.68-300 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Souris 0.78 ng/mL n/a   96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
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Plus Kits ELISA pour Cartilage Acidic Protein 1 partenaires d'interaction

Human Cartilage Acidic Protein 1 (CRTAC1) interaction partners

  1. Confirm the increase of CRTAC1 in cartilage biopsies from OA patients undergoing joint replacement by real-time PCR and immunohistochemistry. Furthermore, we report that proinflammatory cytokines interleukin-1beta and tumor necrosis factor alpha upregulate CRTAC1 expression in primary articular chondrocytes and synovial fibroblasts.

  2. It was shown for the first time the propensity of CRTAC1 to form amyloid-like structures, and it was hypothesized that the aggregating property of CRTAC1 may be related to its disease-association.

  3. These results provided new insights into the mechanism of cataract development, and demonstrated that CRTAC1 could be a potentially novel target for cataract treatment.

  4. CRTAC1 acquired an alternate last exon from the tail-to-tail oriented neighbouring gene in humans resulting in the glycosylated isoform CRTAC1-A which represents a new extracellular matrix molecule of articular cartilage.

  5. in bone fracture patients, 12 proteins were related to bone/cartilage metabolism, including: TGF-beta induced protein IG-H(3), cartilage acidic protein 1, procollagen C proteinase enhancer protein and TGF-beta receptor III.

Mouse (Murine) Cartilage Acidic Protein 1 (CRTAC1) interaction partners

  1. Genetic deletion of Crtac1 significantly inhibited cartilage degradation, osteophyte formation and gait abnormalities of post-traumatic OA in female, but not male, animals undergoing the destabilization of medial meniscus (DMM) surgery.

  2. These data suggest that LOTUS functions as a potent endogenous antagonist for NgR1 when bound by all four known NgR1 ligands.

  3. These findings suggest that the UA/EC region is a functional domain of LOTUS serving for an antagonistic action to NgR1.

  4. found CRTAC1-B(LOTUS)is key molecule for lateral olfactory tract(LOT)formation; NgR1 is LOTUS-binding protein;LOTUS suppressed Nogo-NgR1 binding and Nogo-induced growth cone collapse;suggest endogenous antagonism of NgR1 by LOTUS crucial for LOT formation

Cartilage Acidic Protein 1 (CRTAC1) profil antigène

Antigen Summary

This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CRTAC1

  • cartilage acidic protein 1 (CRTAC1) anticorps
  • cartilage acidic protein 1a (crtac1a) anticorps
  • cartilage acidic protein 1 (crtac1) anticorps
  • cartilage acidic protein 1 (aspip) anticorps
  • cartilage acidic protein 1 (Crtac1) anticorps
  • 2810454P21Rik anticorps
  • ASPIC anticorps
  • ASPIC1 anticorps
  • ASPIP anticorps
  • AW047536 anticorps
  • cb184 anticorps
  • CEP-68 anticorps
  • crtac1 anticorps
  • Crtac1B anticorps
  • Lotus anticorps
  • MGC146658 anticorps
  • sb:cb184 anticorps
  • W307 anticorps
  • zgc:165343 anticorps

Protein level used designations for CRTAC1

cartilage acidic protein 1 , ASPIC , cartilage acidic protein 1a , acidic secreted protein in cartilage , chondrocyte expressed protein 68 kDa CEP-68 , 68 kDa chondrocyte-expressed protein , CEP-68 , protein CRTAC1-B

GENE ID SPECIES
425346 Gallus gallus
450660 Pan troglodytes
559626 Danio rerio
707486 Macaca mulatta
779826 Xenopus (Silurana) tropicalis
100021408 Monodelphis domestica
100060874 Equus caballus
100125469 Oryzias latipes
100352703 Oryctolagus cuniculus
100476456 Ailuropoda melanoleuca
100593381 Nomascus leucogenys
55118 Homo sapiens
72832 Mus musculus
608827 Canis lupus familiaris
100139581 Bos taurus
171438 Rattus norvegicus
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