Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) Kits ELISA

The protein encoded by E2IG3 may interact with p53 and may be involved in tumorigenesis. De plus, nous expédions Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Anticorps (136) et Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Protéines (6) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
E2IG3 26354 Q9BVP2
E2IG3 30877 Q8CI11
E2IG3 290556 Q811S9
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Top Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Souris < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
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Plus Kits ELISA pour Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) partenaires d'interaction

Zebrafish Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish.

Human Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. GNL3 promotes the EMT in colon cancer by activating the Wnt/betacatenin signaling pathway. GNL3 is upregulated in colon cancer and plays an important role in tumor growth, invasion and metastasis.

  2. In addition, migration and invasion demonstrated significant inhibition in Nucleostemin-deficient cells. Furthermore, the knockdown of Nucleostemin dramatically suppressed xenograft progression in BALB/c nude mice. Our findings suggest that Nucleostemin is associated with malignancy in an ovarian cancer SKOV-3 cell line.

  3. Identified a positive correlation between up-regulation of nucleostemin and human glioma cell proliferation and that knocking-down nucleostemin alleviated glioma proliferation by reducing beta-Catenin transportation into the nucleus.

  4. Relative expression of GNL3 in synovial tissue and fluid samples was significantly higher in the osteoarthritic group as compared to the non-osteoarthritic group.

  5. The expression level of GNL3 was examined in 89 human gastric cancer samples using immunohistochemistry (IHC) staining. GNL3 in gastric cancer tissues was significantly upregulated compared with paracancerous tissues.

  6. Study demonstrated overexpression of NS in most hepatocellular carcinoma tissues compared with their matched surrounding tissues, and silencing NS promoted UV- and serum starvation-induced apoptosis of MHCC97H and Bel7402 cells.

  7. over-expression of GNL3 and SKA3 in the PC-3 human prostate cancer cell line decreased in vitro cell migration and invasion

  8. p53 activation by inauhzin via inhibiting SIRT1, also inhibits cellular IMPDH2 activity, reduces the levels of cellular GTP and GTP-binding nucleostemin, thus representing in a new anti-cancer strategy.

  9. overexpression of NS suppressed ARF polyubiquitination by its E3 ligase Ubiquitin Ligase for ARF and elongated its half-life, whereas knockdown of NS led to the decrease of ARF levels

  10. Silence of nucleostemin inhibit cell proliferation through up-regulating p21 expression and nucleostemin may be involved in the pathogenesis of esophageal squamous cell carcinoma.

  11. It is concluded that nucleostemin expression could not be specific in a certain type of cells in colon cancer cell line HT29.

  12. Data shows that the NS protein expression status was positively correlated with both ER and HER2 status and was a powerful prognostic factor.

  13. Based on our results, NS overexpression seems to have a causative role in gastric tumorigenesis and/or progression, and it could be considered as a potential tumor marker for diagnosis, molecular classification

  14. Gene expression profiling analysis revealed that cell cycle regulators and nucleotide metabolism-related genes were highly enriched in a gene set associated with leukaemia-initiating capacity that we termed the 'leukaemia stem cell gene signature'.

  15. cis-acting regulatory polymorphisms acting on GNL3 and SPCS1 contribute to the OA association signal at chromosome 3p21, and these genes therefore merit further investigation.

  16. Nucleostemin can be used for tracking minimal residual disease and is a helpful guide for treatment.

  17. NS functions downstream of Myc as a rate-limiting regulator of cell proliferation and transformation.

  18. The nucleostemin(NS)could promote the recruitment of PML-IV to SUMOylated TRF1 in TA( ) and ALT cells.

  19. NS undergoes a ubiquitin- and MDM2-independent proteasomal degradation when intracellular GTP levels are markedly reduced

  20. Nucleostemin is expressed in Glioblastoma-cancer stem cells isolated from patient samples, and that its expression, conversely to what it has been described for ordinary stem cells, does not disappear when cells are differentiated.

Mouse (Murine) Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Nucleostemin expression participates in the preservation of the viability and integrity of embryonic stem cells.

  2. nucleostemin protects hematopoietic stem cells (HSCs) from DNA damage accumulation and is required for the maintenance of HSCs.

  3. Mechanistic studies performed in mouse embryonic fibroblast cells showed that loss of nucleostemin triggers DNA damage and growth arrest independently of the p53 status or rRNA synthesis

  4. NS plays a critical role in regeneration of both hepatic precursor cells and hepatocytes in response to liver injury.

  5. Nucleostemin in the maintenance of ESC self-renewal, demonstrate the importance of rapid transit through G1 for this process, and expand the known classes of reprogramming factors.

  6. NS functions downstream of Myc as a rate-limiting regulator of cell proliferation and transformation.

  7. NS undergoes a ubiquitin- and MDM2-independent proteasomal degradation when intracellular GTP levels are markedly reduced

  8. a complex composed of TERT, BRG1, and NS/GNL3L maintains the function of tumor initiating cells

  9. Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.

  10. Findings establish the tumor-initiating and molecular features of NS-enriched mammary tumor cells, suggesting that NS may offer a valuable therapeutic target.

  11. skeletal muscle cell differentiation has a unique expression profile of NS in that it is continuously expressed during differentiation.

  12. Data show that the NS-GFP system provides a powerful tool to elucidate stem cell biology in normal and malignant tissues.

  13. analysis of nucleolar localization of stem cell protein nucleostemin

  14. Nucleostemin has a unique ability, derived from an ancestral function, to control the proliferation rate of stem/progenitor cells in vivo independently of p53.

  15. Has roles in establishing early embryogenesis and delaying cellular senescence of embryonic fibroblasts.

  16. Transgenic mice were created that expressed green fluorescent proteins from the genomic locus of nucleostemin using the bicistronic or the ATG-fusion approach.

  17. Nucleostemin expression in cardiomyocytes is induced by fibroblast growth factor-2 and accumulates in response to Pim-1 kinase activity.

  18. NS is a marker of undifferentiated status in the germ cell lineage during prepubertal spermatogenesis

  19. Loss of nucleostemin results in reduced cell proliferation and increased apoptosis in both embryonic stem (ES) cells and ES cell-derived neural stem/progenitor cells.

Xenopus laevis Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Nucleostemin functions in early amphibian development to control cell proliferation of neural progenitor cells.

Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) profil antigène

Antigen Summary

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with E2IG3

  • guanine nucleotide binding protein-like 3 (nucleolar) (gnl3) anticorps
  • G protein nucleolar 3 (GNL3) anticorps
  • guanine nucleotide binding protein-like 3 (nucleolar) (Gnl3) anticorps
  • G protein nucleolar 3 (Gnl3) anticorps
  • guanine nucleotide binding protein-like 3 (nucleolar) L homeolog (gnl3.L) anticorps
  • BC037996 anticorps
  • C77032 anticorps
  • E2IG3 anticorps
  • id:ibd2914 anticorps
  • NNP47 anticorps
  • Ns anticorps
  • nstm anticorps
  • wu:fb38a04 anticorps
  • wu:fc55d07 anticorps
  • zgc:123093 anticorps

Protein level used designations for E2IG3

guanine nucleotide-binding protein-like 3 , nucleostemin , nucleostemin-like protein , guanine nucleotide binding protein-like 3 (nucleolar) , guanine nucleotide-binding protein-like 3-like , E2-induced gene 3 protein , estradiol-induced nucleotide binding protein , novel nucleolar protein 47 , nucleolar GTP-binding protein 3

GENE ID SPECIES
321897 Danio rerio
394765 Xenopus (Silurana) tropicalis
415897 Gallus gallus
100155235 Sus scrofa
100231668 Taeniopygia guttata
100458988 Pongo abelii
26354 Homo sapiens
30877 Mus musculus
100685258 Canis lupus familiaris
506152 Bos taurus
290556 Rattus norvegicus
380340 Xenopus laevis
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