anti-Hemoglobin, gamma A (HBG1) Anticorps

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. De plus, nous expédions HBG1 Protéines (14) et HBG1 Kits (10) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HBG1 94164  
HBG1 3047 P69891
HBG1    
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Top anti-HBG1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 50 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB HBG1 Antibody (Center) (ABIN657619) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the HBG1 antibody detected the HBG1 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Hemoglobin gamma A Antibody (JM84-10)  - Staining HBG1/2 in D3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Immunocytochemistry/Immunofluorescence: Hemoglobin gamma A Antibody (JM84-10)  - Staining HBG1/2 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 100 μL Connectez-vous pour afficher 34 Days
$373.75
Détails
Humain Lapin Inconjugué WB Western blot analysis of HBG1 using rabbit polyclonal HBG1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene. Western blot analysis in K562 cell line lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (33.04 KDa) . 50 μL Connectez-vous pour afficher 11 to 12 Days
$305.71
Détails
Humain Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Humain Lapin HRP ELISA, IHC, IHC (p) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μg Connectez-vous pour afficher 11 to 14 Days
$463.83
Détails
Humain Souris Inconjugué ELISA   100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Lapin Biotin ELISA, IHC, IHC (p) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μg Connectez-vous pour afficher 11 to 14 Days
$581.17
Détails
Humain Lapin FITC ELISA, IHC, IHC (p) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μg Connectez-vous pour afficher 11 to 14 Days
$581.17
Détails
Humain Souris Inconjugué ELISA Detection limit for recombinant GST tagged HBG1 is 3 ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails

HBG1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Rat (Rattus)

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Human , , ,
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Mouse (Murine)

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anti-HBG1 Anticorps mieux référencés

  1. Human Polyclonal HBG1 Primary Antibody pour ELISA, WB - ABIN561232 : Lee, Kim, Byrnes, de Vasconcellos, Noh, Rabel, Meier, Miller: A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors. dans PLoS ONE 2013 (PubMed)

Plus d’anticorps contre HBG1 partenaires d’interaction

Human Hemoglobin, gamma A (HBG1) interaction partners

  1. A significant relationship between two variations (+25G/A and -499T/A) in Agamma gene promotor and fetal hemoglobin levels was observed.

  2. study describes the characterization of the rs368698783 (+25 G->A) polymorphism of the Agamma-globin gene associated in beta(0)39 thalassemia patients with high HbF in erythroid precursor cells

  3. Introduction of the British HPFH mutation into the fetal globin promoter in a human cell model causes elevated fetal globin expression. The British HPFH mutation creates a de novo binding site both in vitro and in vivo for the potent erythroid activator KLF1 (Montrer KLF1 Anticorps).

  4. A Ly1 antibody reactive (LYAR)-binding motif disruptive regulatory single-nucleotide polymorphisms rs368698783 (G/A) from LD block 5 in the proximal promoter of hemoglobin subunit gamma 1 (HBG1) was found to be a significant predictor for beta-thalassemia clinical severity.

  5. Study found a novel polymorphism of the A-gamma-globin gene in four families with b0-thalassemia and high levels of HbF expression. Additionally, evidence suggesting that the Ac-globin gene +25(G-A) polymorphism decreases the efficiency of the interaction between this sequence and specific DNA binding protein (Montrer UBE2V1 Anticorps) complexes.

  6. These data confirm the regulatory role of the HBG1: g.-225_-222 region that exerts its effect under conditions of erythropoietic stress characteristic for beta-thal patients.

  7. results suggest that KLF1 directly regulates the beta-globin gene, but probably has less direct impact on expression of the gamma-globin gene in fetal erythroblasts

  8. Data show that the ancestral allele C at rs2855126, located upstream of gamma-globin (HBG1) is associated with increased serum uric acid levels.

  9. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  10. a successful induction of gamma-globin includes a reduction in BCL11A (Montrer BCL11A Anticorps), KLF1 (Montrer KLF1 Anticorps) and TAL1 (Montrer TAL1 Anticorps) expression.

HBG1 profil antigène

Profil protéine

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with HBG1

  • hemoglobin subunit gamma 2 (HBG2) anticorps
  • hemoglobin subunit gamma 1 (Hbg1) anticorps
  • hemoglobin subunit epsilon 1 (HBE1) anticorps
  • hemoglobin subunit gamma 1 (HBG1) anticorps
  • hemoglobin, gamma G (HBG2) anticorps
  • Hbb-y anticorps
  • Hbe1 anticorps
  • HBG1 anticorps
  • HBG2 anticorps
  • HBGA anticorps
  • HBGR anticorps
  • HSGGL1 anticorps

Protein level used designations for HBG1

epsilon 3 globin , hemoglobin Y beta-like embryonic chain , hemoglobin Y, beta-like embryonic chain , hemoglobin, epsilon 1 , hemoglobin, gamma A , A-gamma globin , gamma A hemoglobin , gamma globin , gamma-1-globin , hb F Agamma , hemoglobin gamma-1 chain , hemoglobin gamma-a chain , hemoglobin subunit gamma-1 , hemoglobin, gamma, regulator of , epsilon-globin , hemoglobin, gamma G

GENE ID SPECIES
100438895 Pongo abelii
94164 Rattus norvegicus
100137314 Papio anubis
3047 Homo sapiens
450979 Pan troglodytes
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