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The protein encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. De plus, nous expédions MAP/microtubule Affinity-Regulating Kinase 3 Anticorps (122) et MAP/microtubule Affinity-Regulating Kinase 3 Protéines (13) et beaucoup plus de produits pour cette protéine.
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Authors identified a regulatory switch controlled by MARK3 that couples microtubules to the actin cytoskeleton to establish epithelial cell polarity through ARHGEF2 (Montrer ARHGEF2 Kits ELISA).
findings indicate that brain PP-1I associates with and is regulated by the associated protein kinases C-TAK1 and PFTK1
We have shown that serum ALP (Montrer ALP Kits ELISA) levels modified the association of MARK3 with bone mineral density in osetoporosis for Chinese patients.
interaction between Mitf (Montrer MITF Kits ELISA) and C-TAK1 was demonstrated.
results show that LKB1 (Montrer STK11 Kits ELISA) can direct the phosphorylation of the serine-threonine kinase PAR1A
identify sequence motifs required for stable C-TAK1 association and substrate phosphorylation
The C-TAK1/p78 (Montrer MCRS1 Kits ELISA) constitutively associates with and phosphorylates KSR1 (Montrer KSR1 Kits ELISA) generating a 14-3-3 (Montrer YWHAQ Kits ELISA) binding site.
Data show that the protein kinase (Montrer CDK7 Kits ELISA) Cdc25 (Montrer RASGRF1 Kits ELISA) C-associated kinase 1 (C-TAK1) is a binding partner and a substrate of Pim-1 (Montrer PIM1 Kits ELISA), and suggest a role for Pim-1 (Montrer PIM1 Kits ELISA) as a positive regulator at the G(2)/M transition of the cell cycle.
14-3-3 (Montrer YWHAQ Kits ELISA) binding to MARK3 is dependent on phosphorylation.
Class IIa histone deacetylases (HDACs) are subjected to signal-independent nuclear export that relies on their constitutive phosphorylation. EMK and C-TAK1, are identified as regulators of this process.
Knockout mice were protected against high-fat diet-induced obesity and displayed attenuated weight gain, complete resistance to hepatic steatosis, and improved glucose handling with decreased insulin (Montrer INS Kits ELISA) secretion.
Approximately 50 additional residues preceding the previously defined KA1 (Montrer GRIK4 Kits ELISA) domain are required for MARK3 proper folding.
PAR-1 (Montrer F2R Kits ELISA) RNA rescues neural cell markers in embryos in which noncanonical Wnt (Montrer WNT2 Kits ELISA) signaling has been blocked. Novel roles for Wnt11R (Montrer WNT11 Kits ELISA) and PAR-1 (Montrer F2R Kits ELISA) were identified in neural cell specification. An unexpected connection was shown between morphogenesis and cell fate.
PAR-1 (Montrer F2R Kits ELISA) is a crucial regulator of the balance between symmetric (two superficial daughters) and asymmetric (one superficial and one deep daughter) cell divisions
The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene.
MAP/microtubule affinity-regulating kinase 3
, MAP/microtubule affinity-regulating kinase 3-like
, ELKL motif kinase 2
, cdc25C-associated protein kinase 1
, protein kinase STK10
, ser/Thr protein kinase PAR-1
, serine/threonine-protein kinase p78
, EMK2/MARK3 serine-threonine protein kinase
, Ser/Thr protein kinase PAR-1A