anti-One Cut Homeobox 1 (ONECUT1) Anticorps

ONECUT1 encodes a member of the Cut homeobox family of transcription factors. De plus, nous expédions One Cut Homeobox 1 Kits (17) et One Cut Homeobox 1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ONECUT1 15379 O08755
ONECUT1 25231 P70512
ONECUT1 3175 Q9UBC0
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Top anti-One Cut Homeobox 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 60 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-ONECUT1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Immunohistochemistry with Human Brain, cerebellum tissue at an antibody concentration of 5.0ug/ml using anti-ONECUT1 antibody 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ONECUT1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB Sample Type: Frozen section of mouse embryo at et12.5Primary Dilution: 1:500Secondary Dilution: 1:2000Antigen Retrevial method: Citrate buffer (pH=6) Image Submitted By: Fré,dé,ric ClotmanUniversité, catholique de Louvain 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IHC (fro), IHC (p), WB Anti-HNF6 antibody, IHC(P) IHC(P): Rat Liver Tissue Anti-HNF6 antibody, IHC(F) IHC(F): Rat Liver Tissue 100 μg 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of ONECUT1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). This demonstrates the ONECUT1 antibody detected the ONECUT1 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ONECUT1 antibody ABIN462211 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Spleen (formalin-fixed, paraffin-embedded) stained with ONECUT1 antibody ABIN462211 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 100 μL 11 to 14 Days
$727.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, WB   100 μL 11 to 13 Days
$335.04
Détails
Humain Lapin Inconjugué WB Western blot analysis in HL-60 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails

anti-One Cut Homeobox 1 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal ONECUT1 Primary Antibody pour IHC, WB - ABIN2780599 : Huang, Mei, Yu, Zhang, Han, Jiang, Zhou: Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig. dans Acta histochemica 2009 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal ONECUT1 Primary Antibody pour WB - ABIN2780598 : Jiang, Zhang, Kayed, Zheng, Giese, Friess, Kleeff: Loss of ONECUT1 expression in human pancreatic cancer cells. dans Oncology reports 2007 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre One Cut Homeobox 1 partenaires d’interaction

Mouse (Murine) One Cut Homeobox 1 (ONECUT1) interaction partners

  1. Pdx1 and Oc1 cooperativity in Multipotent pancreatic progenitors impacts postnatal beta-cell maturation and function. Here a model of Pdx1-Oc1 double heterozygosity was used to investigate the impact of haploinsufficiency for both of these factors on postnatal beta-cell maturation, function, and adaptability.

  2. These results suggest that Oc1 and Pdx1 cooperate prior to their divergence, in pancreatic progenitors, to allow for proper differentiation and functional maturation of beta cells.

  3. Expression of motor neuron effector genes is maintained by transient enhancers bound by Isl1/Lhx3 in nascent motor neurons and Isl1/Onecut1 in maturing hypaxial motor neurons.

  4. Data show that growth hormone (GH)/lipopolysaccharides (LPS) co-treatment enhanced hepatocyte nuclear factor 6 (Hnf6) expression with corresponding attenuation of apoptosis in WT-derived hepatocytes, but not in KO hepatocytes.

  5. HNF6 binding was sex independent at a majority of binding sites, and HNF6 peaks were frequently associated with cobinding by multiple other liver transcription factors, consistent with HNF6 playing a global regulatory role in both male and female liver.

  6. with Lmx1a to promote ventral midbrain neural stem cells differentiation into dopamine neuron through Wnt1-Lmx1a pathway.

  7. Onecut1 and Onecut2 have roles in operating downstream of Pax6 to regulate horizontal cell development

  8. similar to Onecut1, Onecut2 is also necessary for the formation of normal numbers of horizontal cells in the developing retina.

  9. identified downstream genes of Oc1 and Oc2 that shows that the onecut factors suppress the production of the late cell type, rods, indicating that the two factors contribute to the competence of retinal progenitor cells for early retinal cell fates

  10. Sex-dependent growth hormone secretion patterns affect the expression of HNF6 in liver.

  11. Liver cell plasticity is competent for regeneration of intrahepatic bile duct independent of Notch signaling via Rbpj and Hnf6.

  12. in Hnf6-/- mice, the organization of Purkinje cells became abnormal during a second phase of their development.

  13. Insight on the role of HNF6 in pancreatic cancer development could lead to its use as a biomarker for early detection and prognosis.

  14. Findings suggest that Onecut1 suppresses MafA gene expression through the Foxa2-binding site.

  15. Let-7b, miR-495, and their targets constitute a gene network that is required to establish and maintain pancreatic acinar cell differentiation. Let-7b and miR-495 repress HNF6 and are expressed in developing acini.

  16. this study showed that Onecut1 is essential for horizontal cell genesis and retinal integrity in mice.

  17. Onecut1 suppresses rod photoreceptor genesis.

  18. HNF-6 controls in spinal motor neurons a genetic program that coordinates the formation of hindlimb neuromuscular junctions

  19. HNF6 and Sox9 are new biomarkers of pancreatic acinar-to-ductal metaplasia and constitute candidate targets for preventive treatment in cases when acinar-to-ductal metaplasia may lead to cancer.

  20. Onecut1 and Onecut2 are expressed in both developing and mature horizontal cells of the retina.

Human One Cut Homeobox 1 (ONECUT1) interaction partners

  1. Reduced HNF6 expression is associated with metastasis of cholangiocarcinoma.

  2. HNF6 is a novel host factor that can restrict hepatitis B virus replication via both transcriptional and posttranscriptional mechanisms.

  3. The negative correlation between HNF6 expression and pancreatic cancer progression suggests that HNF6 maintains pancreatic epithelial homeostasis, and that its loss contributes to the progression from intraepithelial neoplasms to ductal adenocarcinoma.

  4. HNF6 plays an important role in the gene regulation of CYP3A4 during development from the fetal period to the postnatal period.

  5. HNF6 inhibits EMT, cell migration, and invasive growth through a mechanism involving the transcriptional activation of p53.

  6. Mutations at the -5/-6 site of the F9 promotor account for the majority of hemophilia B Leyden cases and disrupt the binding of ONECUT1 and ONECUT2.

  7. HNF6 and Sox9 are new biomarkers of pancreatic acinar-to-ductal metaplasia and constitute candidate targets for preventive treatment in cases when acinar-to-ductal metaplasia may lead to cancer.

  8. Hepatocyte nuclear factor 6 is one of the liver-enriched transcription factors, it utilizes the bipartite onecut-homeodomain sequence to localize to the nuclear compartment and bind specific DNA sequences of numerous target gene promoters

  9. functional knockdown of FOXA2 recovered HNF6 activity and inhibited growth of tumor-cells and may possibly represent a novel therapeutic target in primary and secondary liver malignancies

  10. HNF6 has a role as a coactivator protein to potentiate the transcriptional activity of another liver factor, FoxA2

  11. These findings define a precursor cellular stage of the embryonic pancreas and place Hnf1beta in a genetic hierarchy that regulates the generation of pancreatic endocrine cells.

  12. identifed systematically the genes occupied by the transcriptional regulators HNF1alpha, HNF4alpha, and HNF6, together with RNA polymerase II in human liver and pancreatic islets

  13. HNF6 protein stability is controlled by CBP acetylation

  14. A comparision of gene expression patterns induced by hepatic nuclear factors, HNF6, HNF4alpha and HNF1beta, in a pancreatic beta-cell line.

  15. HNF6 DNA binding is selectively abrogated through lack of post-translational modification and interaction with FOXA2. Targeting of FOXA2 and HNF6 may therefore enable mechanism-based therapy for colorectal liver metastases

  16. ONECUT1 expression is lost in pancreatic cancer cells, suggesting a tumor suppressor function in this malignancy.

  17. Results suggest that HNF-6 is a novel target of small heterodimer partner in the regulation of gluconeogenesis.

Zebrafish One Cut Homeobox 1 (ONECUT1) interaction partners

  1. findings identify vps33b is a novel downstream target gene of the hnf6/vhnf1 pathway that regulates bile duct development in zebrafish

One Cut Homeobox 1 (ONECUT1) profil antigène

Profil protéine

This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ONECUT1

  • one cut domain, family member 1 (Onecut1) anticorps
  • one cut homeobox 1 (Onecut1) anticorps
  • one cut homeobox 1 (ONECUT1) anticorps
  • one cut homeobox 1 (onecut1) anticorps
  • D9Ertd423e anticorps
  • Hfh12 anticorps
  • HNF-6 anticorps
  • HNF-6a anticorps
  • HNF6 anticorps
  • HNF6A anticorps
  • Hnf6b anticorps
  • OC-1 anticorps
  • oc1 anticorps
  • onecut1l anticorps
  • zgc:65904 anticorps
  • zgc:77450 anticorps

Protein level used designations for ONECUT1

HNF-3/forkhead homolog 12 , hepatic nuclear factor 6 , hepatocyte nuclear factor 6 , one cut homeobox 1 , HNF-6 , one cut domain family member 1 , one cut domain, family member 1 , hepatocyte nuclear factor 6, alpha , hepatocyte nuclear factor 6 alpha , hnf-6 , hnf6 , one cut domain, family member 1, like

GENE ID SPECIES
15379 Mus musculus
25231 Rattus norvegicus
3175 Homo sapiens
503584 Bos taurus
393545 Danio rerio
487558 Canis lupus familiaris
100723740 Cavia porcellus
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