Profil protéine

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

Gene names and symbols associated with PEG10

• paternally expressed 10 (PEG10) anticorps
• paternally expressed 10 (Peg10) anticorps

• AA407948 anticorps
• Edr anticorps
• HB-1 anticorps
• Mar2 anticorps
• Mart2 anticorps
• Afficher tous les alias de synonymes
• MEF3L anticorps
• MyEF-3 anticorps
• RGAG3 anticorps

Protein level used designations for PEG10

MEF3 like 1 , MEF3-like protein 1 , embryonal carcinoma differentiation regulated , embryonal carcinoma differentiation-regulated protein , mammalian retrotransposon-derived protein 2 , myelin expression factor 3-like protein 1 , paternally expressed gene 10 protein , retrotransposon gag domain containing 3 , retrotransposon gag domain-containing protein 3 , retrotransposon-derived gag-like polyprotein , retrotransposon-derived protein PEG10 , ty3/Gypsy-like protein , MyEF-3 like , embryonal carcinoma differentiation regulated protein , myelin expression factor 3 , paternally expressed 10 , LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10 , retrotransposon-derived protein PEG10-like