anti-Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Anticorps

The protein encoded by KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. De plus, nous expédions KCNN4 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
KCNN4 3783 O15554
KCNN4 65206  
KCNN4 16534 O89109
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Top anti-KCNN4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 78 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-KCNN4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: KCNN4 Antibody [NBP2-33694] - breast cancer Immunohistochemistry: KCNN4 Antibody [NBP2-33694] - Immunohistochemical staining of human smooth muscle shows moderate cytoplasmic positivity in smooth muscle cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué IF, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p) Anti-KCNN4 antibody  ABIN1048992 IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC (p) Anti-KCNN4 antibody  ABIN1048993 IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Boeuf (Vache) Chèvre Inconjugué IHC (p) Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué IHC (p), WB   100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB Anti-KCNN antibody,  Western blotting All lanes: Anti KCNN() at 0.5ug/ml WB: HUT Whole Cell Lysate at 40ug Predicted bind size: 60KD Observed bind size: 60KD 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué WB KCNN4 (KCA3.1) Polyclonal Antibody 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$379.50
Détails

KCNN4 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-KCNN4 Anticorps mieux référencés

  1. Human Polyclonal KCNN4 Primary Antibody pour WB - ABIN948055 : Wong, Roberts, Randall: Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions? dans British journal of pharmacology 2014 (PubMed)

  2. Human Polyclonal KCNN4 Primary Antibody pour IF (p), IHC (p) - ABIN719786 : Zhang, Yang, Yin, Yi, Shen, Zhao, Zhu, Liu: Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells. dans PLoS ONE 2016 (PubMed)

  3. Human Polyclonal KCNN4 Primary Antibody pour IHC, IHC (p) - ABIN4328499 : Rabjerg, Oliván-Viguera, Hansen, Jensen, Sevelsted-Møller, Walter, Jensen, Marcussen, Köhler: High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival. dans PLoS ONE 2015 (PubMed)

Plus d’anticorps contre KCNN4 partenaires d’interaction

Pig (Porcine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) interaction partners

  1. Blockade of K(Ca)3.1 by delivery of TRAM (Montrer TRAM1 Anticorps)-34 via balloon catheter prevented smooth muscle phenotypic modulation and limited subsequent restenosis in a swine model.

Human Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) interaction partners

  1. Tumor suppressor miR (Montrer MLXIP Anticorps)-497-5p down-regulates KCa3.1 expression and contributes to the inhibition of angiosarcoma malignancy development.

  2. We identified a two-gene signature including KCNN4 and S100A14 (Montrer S100A14 Anticorps) which was related to recurrence in optimally debulked serous ovarian carcinoma patients

  3. Human arrhythmogenic calmodulin mutations impede the activation of SK2 (Montrer KCNN2 Anticorps) channels in human embryonic kidney 293 cells.

  4. This study found a very substantial functional expression of KCa3.1 channels in microglia from adult epilepsy patients.

  5. Data show that RNAi-mediated knockdown of KCa3.1 and/or TRPC1 (Montrer TRPC1 Anticorps) leads to a significant decrease in cell proliferation due to cell cycle arrest in the G1 phase.

  6. Higher epithelial KCNN4 expression was closely correlated with advanced TNM (Montrer ODZ1 Anticorps) stages and predicted a poor prognosis in patients with pancreatic ductal adenocarcinoma.

  7. Here, the authors demonstrate that phosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channel.

  8. This work demonstrates the critical role of SK4 Ca(2 (Montrer CA2 Anticorps)+)-activated K(+) channels in adult pacemaker function.

  9. Implicating both KCa1.1 (Montrer KCNMA1 Anticorps) and KCa3.1 channels.

  10. Blocking KCa3.1 suppresses plaque instability in advanced stages of atherosclerosis by inhibiting macrophage polarization toward an M1 phenotype.

Cow (Bovine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) interaction partners

  1. Blood brain barrier endothelial cells exhibit KCa3.1 protein and activity.

Mouse (Murine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) interaction partners

  1. Following differentiation with LPS (Montrer TLR4 Anticorps) or a combination of LPS (Montrer TLR4 Anticorps) and IFN-gamma (Montrer IFNG Anticorps) microglia exhibited high KV 1.3 current densities ( approximately 50 pA/pF at 40 mV) and virtually no KCa (Montrer CSN3 Anticorps) 3.1 and Kir (Montrer GEM Anticorps) currents, while microglia differentiated with IL-4 (Montrer IL4 Anticorps) exhibited large Kir (Montrer GEM Anticorps) 2.1 currents ( approximately 10 pA/pF at -120 mV). KCa (Montrer CSN3 Anticorps) 3.1 currents were generally low

  2. Deletion of KCa3.1 reduced astrogliosis and rescued memory loss induced by intrahippocampal Abeta1-42 peptide injection.

  3. Dynamic coupling between TRPV4 (Montrer TRPV4 Anticorps) and Ca(2 (Montrer CA2 Anticorps)+)-activated SK1 (Montrer SPHK1 Anticorps)/3 and IK1 K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 (Montrer KCNMA1 Anticorps) in kidney collecting duct cells.

  4. Blocking KCa3.1 suppresses plaque instability in advanced stages of atherosclerosis by inhibiting macrophage polarization toward an M1 phenotype.

  5. enhanced KCa (Montrer CSN3 Anticorps) 3.1 activity may compensate for decreased nitric oxide signaling during vascular aging.

  6. Findings highlight a novel role for intermediate-conductance calcium-activated potassium channel (Montrer KCNAB2 Anticorps) (KCa3.1) in phenotypic modulation of reactive astrocytes and in astrocyte mobilization in response to mechanical stress, providing a potential target for therapeutic intervention in brain injuries.

  7. alpha1D Ca and SK4 channels are coupled in the atria, and deletion of alpha1D leads to decreased SK4 mRNA and BNP (Montrer BNC2 Anticorps) secretion providing evidence for a novel role of alpha1D in atrial endocrine function

  8. KCa3.1 blockade protects against cisplatin-induced acute kidney injury through the attenuation of apoptosis by interference with intrinsic apoptotic and endoplasmic reticulum stress-related mediators.

  9. The results suggest that KCa3.1 activation contributes to dysfunctional tubular autophagy in diabetic nephropathy through PI3K/Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) signaling pathways.

  10. These results indicate that IK1 channels do not mediate the a slow afterhyperpolarization in pyramidal neurons.

KCNN4 profil antigène

Profil protéine

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Gene names and symbols associated with KCNN4

  • potassium calcium-activated channel subfamily N member 4 (KCNN4) anticorps
  • potassium calcium-activated channel subfamily N member 4 (Kcnn4) anticorps
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (Kcnn4) anticorps
  • hIKCa1 anticorps
  • hKCa4 anticorps
  • hSK4 anticorps
  • IK1 anticorps
  • IKCA1 anticorps
  • KCa3.1 anticorps
  • KCA4 anticorps
  • mIKCa1 anticorps
  • rKCNN4c anticorps
  • rSK4 anticorps
  • SK4 anticorps
  • SKCas anticorps

Protein level used designations for KCNN4

intermediate conductance calcium-activated potassium channel protein 4 , intermediate-conductance calcium-activated potassium channel , intermediate conductance calcium-activated potassium channel protein 1 , potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 , intermediate conductance calcium-activated potassium channel protein 4-like , SKCa 4 , SKCa4 , putative Gardos channel , putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel , IK1 , KCa4 , SK4 , intermediate conductance K channel , intermediate-conductance Ca-activated K channel , potassium intermediate-small conductance calcium-activated channel subfamily N member 4

GENE ID SPECIES
397081 Sus scrofa
456098 Pan troglodytes
100379254 Cavia porcellus
100391934 Callithrix jacchus
100468357 Ailuropoda melanoleuca
100593199 Nomascus leucogenys
3783 Homo sapiens
65206 Rattus norvegicus
534591 Bos taurus
484464 Canis lupus familiaris
16534 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-KCNN4 (KCNN4) Anticorps
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