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May play a role in the proliferation or differentiation of keratinocytes (By similarity).. De plus, nous expédions serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 13 Kits (9) et serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 13 Protéines (3) et beaucoup plus de produits pour cette protéine.
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These data demonstrate that RUNX1 (Montrer RUNX1 Anticorps) is an important regulator of SERPINB13 and cathepsin K (Montrer CTSK Anticorps) activity.
Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis.
hurpin is expressed in skin and has a possible role in inflammatory processes or the regulation of endogenous or pathogen-derived proteinase activity
Down-regulation of SERPINB13 is associated with head and neck squamous cell carcinoma
the expression of hurpin was confined mainly to the basal layer in normal skin samples, whereas hurpin was overexpressed and redistributed in diseased skin
Downregulation of SERPINB13 protein expression in HNSCC is positively associated with poor clinical outcome. Therefore, SERPINB13 seems to act as an important protease inhibitor involved in the progression of HNSCC.
results suggest an important role of Cat L (Montrer CTSL1 Anticorps) regulation by hurpin which might be of clinical relevance in human skin diseases
May play a role in the proliferation or differentiation of keratinocytes (By similarity).
, UV-B repressed sequence, HUR 7
, haCaT UV-repressible serpin
, peptidase inhibitor 13
, protease inhibitor 13 (hurpin, headpin)
, proteinase inhibitor 13
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13
, serpin B13
, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
, serpin peptidase inhibitor, clade B (ovalbumin), member 13
, serpin peptidase inhibitor, clade B, member 13
, serpin B13-like
, serpin peptidase inhibitor, clade B (ovalbumin), member 5
, serine proteinase inhibitor, clade B, member 13