TYK2 anticorps (N-Term)

N° du produit ABIN1077422

Détail du produit anti-TYK2 anticorps

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: At least three isoforms of TYK2 are known to exist, this antibody only detects the two longest isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2.

Isotype: IgG

Information d'application

Indications d'application: TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μg/mL.

Commentaires:

(NT) Tyrosine kinase 2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: TYK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: TYK2 (TYK2 Produits)

Synonymes: anticorps JTK1, anticorps tyrosine kinase 2, anticorps TYK2, anticorps Tyk2

Sujet: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Synonyms: Tyrosine kinase 2, non-receptor tyrosine kinase 2

Poids moléculaire: 131 kDa (calculated)

ID gène: 7297

NCBI Accession: NP_003322

Pathways: Signalistation JAK/STAT, Hepatitis C