Prostaglandin D2 Receptor 2 (PTGDR2) anticorps

N° du produit ABIN1077429

Détail du produit

Antigène: Prostaglandin D2 Receptor 2 (PTGDR2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal PTGDR2 antibody was raised against a 19 amino acid peptide near the center of human PTGDR2.

Isotype: IgG

Information d'application

Indications d'application: PTGDR2 antibody can be used for detection of PTGDR2 by Western blot at 0.5 - 1 μg/mL.

Commentaires:

(IN) Prostaglandin D2 receptor 2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: PTGDR2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détail du antigène

Antigène: Prostaglandin D2 Receptor 2 (PTGDR2)

Autre désignation: PTGDR2 (PTGDR2 Produits)

Synonymes: anticorps CD294, anticorps CRTH2, anticorps DL1R, anticorps DP2, anticorps GPR44, anticorps Crth2, anticorps Grp45, anticorps Ptgdr2, anticorps Gpr44, anticorps prostaglandin D2 receptor 2, anticorps PTGDR2, anticorps Ptgdr2

Sujet: The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
Synonyms: Prostaglandin D2 receptor 2, chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH2, G protein-coupled receptor 44, GPR44, CD294, DL1R, DP2

Poids moléculaire: 43 kDa (calculated)

ID gène: 11251

NCBI Accession: NP_004769

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling