SNCA anticorps (AA 1-140)

N° du produit ABIN1715843

Détail du produit anti-SNCA anticorps

Antigène: SNCA (Synuclein, alpha (SNCA))

Épitope: AA 1-140

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Fonction: Polyclonal Antibody to Synuclein Alpha (SNCa)

Séquence: MGHHHHHHSG SEFELRRQAC - MKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA

Specificité: The antibody is a rabbit polyclonal antibody raised against SNCa. It has been selected for its ability to recognize SNCa in immunohistochemical staining and western blotting.

Réactivité croisée: Souris, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogène: Recombinant Synuclein Alpha (SNCa) corresdonding to Met1~Ala140 with N-terminal His Tag

Isotype: IgG

Information d'application

Indications d'application:

Western blotting: 0.5-2 μg/mL

Immunohistochemistry: 5-20 μg/mL

Immunocytochemistry: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Commentaires:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Date de péremption: 24 months

Références pour anticorps anti-SNCA (ABIN1715843)

Bhattamisra, Shak, Xi, Safian, Choudhury, Lim, Shahzad, Alhakamy, Anwer, Radhakrishnan, Md: "Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease." dans: International journal of pharmaceutics, Vol. 579, pp. 119148, (2020) (PubMed).

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: Synuclein Alpha (SNCA Produits)

Synonymes: anticorps snca, anticorps MGC64356, anticorps LOC619283, anticorps NACP, anticorps alphaSYN, anticorps PARK1, anticorps PARK4, anticorps PD1, anticorps synuclein alpha L homeolog, anticorps alpha-synuclein, anticorps synuclein alpha, anticorps synuclein, alpha, anticorps snca.L, anticorps LOC619283, anticorps SNCA, anticorps Snca

Sujet: SNC-A, aSYN, PD1, PARK1, PARK4, NACP, Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein, Non-A4 component of amyloid precursor

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity