SHP1 anticorps (AA 553-564)

N° du produit ABIN1103855

Détail du produit anti-SHP1 anticorps

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Épitope: AA 553-564

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SHP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Mouse PTPN6. This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2).

Homologie: Percent identity by BLAST analysis: Mouse, Rat, Hamster (100%) Human, Gorilla, Monkey, Marmoset, Panda, Dog, Horse, Pig (92%) Elephant, Opossum (83%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-KASRTSSKHKEE from an internal region of mouse PTPN6 (NP_536858.1, NP_002822.2). Percent identity by BLAST analysis: Mouse, Rat, Hamster (100%), Human, Gorilla, Monkey, Marmoset, Panda, Dog, Horse, Pig (92%), Elephant, Opossum (83%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:128000), WB (0.1 - 0.3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 60-70 kDa band observed in Human Bone Marrow and Liver lysates (calculated MW of 67.6 kDa according to NP_536858.1and NP_002822.2). Recommended concentration: 0.1-0.3 μg/mL.Tested in IHC-P using FFPE human tissues, has not been tested in IHC with mouse samples.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur SHP1

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Autre désignation: PTPN6 / SHP-1 (PTPN6 Produits)

Synonymes: anticorps HCPH, anticorps HPTP1C, anticorps PTP-1C, anticorps SH-PTP1, anticorps SHP-1, anticorps SHP-1L, anticorps SHP1, anticorps DRPLA, anticorps Hcph, anticorps Ptp1C, anticorps me, anticorps motheaten, anticorps Ptph6, anticorps Shp-1, anticorps fj22f05, anticorps wu:fj22f05, anticorps zgc:55501, anticorps ptpn6, anticorps protein tyrosine phosphatase, non-receptor type 6, anticorps protein tyrosine phosphatase, non-receptor type 6 L homeolog, anticorps PTPN6, anticorps Ptpn6, anticorps ptpn6, anticorps ptpn6.L

Sujet: Name/Gene ID: PTPN6
Subfamily: NT2
Family: Protein Phosphatase

Synonyms: PTPN6, HCP, HPTP1C, Hematopoietic cell phosphatase, PTP-1C, SH-PTP1, SHP-1L, SHP-1, Shptp1, HCPH, PTP1C, SHP1

ID gène: 5777

NCBI Accession: NP_536858, NP_002822

UniProt: P29350

Pathways: Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling