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TNFRSF1A anticorps (Internal Region)
TNFRSF1A
Reactivité: Humain, Rat, Porc
WB, EIA
Hôte: Chèvre
Polyclonal
unconjugated
N° du produit ABIN1105784
Détail du produit anti-TNFRSF1A anticorps
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Antigène
Voir toutes TNFRSF1A Anticorps
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Épitope
Tous les épitopes à travers TNFRSF1A Anticorps.
Internal Region
Reactivité
Toutes les réactivités sur TNFRSF1A Anticorps
Humain, Rat, Porc
Hôte
Toutes les hôtes sur TNFRSF1A Anticorps
Chèvre
Clonalité
Toutes les clonalités sur TNFRSF1A Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers TNFRSF1A Anticorps
Cet anticorp TNFRSF1A est non-conjugé
Application
Tous les applications à travers TNFRSF1A Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Séquence
C-SDHEIDRLEL QNGR
Réactivité croisée (Details)
Species reactivity (expected):Rat, Porcine. Species reactivity (tested):Human.
Purification
Affinity Chromatography
Immunogène
Peptide with sequence from the internal region of the protein sequence according to NP_001056.1. Genename: TNFRSF1A
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
0.02 % Sodium Azide 0.2 % BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur TNFRSF1A
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Antigène
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Autre désignation
CD120a / TNFR1 (TNFRSF1A Produits )
Synonymes
anticorps CD120a, anticorps FPF, anticorps MS5, anticorps TBP1, anticorps TNF-R, anticorps TNF-R-I, anticorps TNF-R55, anticorps TNFAR, anticorps TNFR1, anticorps TNFR1-d2, anticorps TNFR55, anticorps TNFR60, anticorps p55, anticorps p55-R, anticorps p60, anticorps TNF-R1, anticorps TNF-alphaR1, anticorps TNFRI, anticorps TNFRp55, anticorps TNFalpha-R1, anticorps Tnfr-2, anticorps Tnfr1, anticorps fpf, anticorps tbp1, anticorps p55-r, anticorps tnf-r, anticorps tnfar, anticorps tnfr1, anticorps cd120a, anticorps tnfr55, anticorps tnfr60, anticorps xtnfr1, anticorps wu:fj65b10, anticorps zgc:85914, anticorps TNFR I, anticorps TNFRSF1A, anticorps TNFA, anticorps cTNF, anticorps TNF receptor superfamily member 1A, anticorps tumor necrosis factor receptor superfamily, member 1a, anticorps TNF receptor superfamily member 1A S homeolog, anticorps tumor necrosis factor, anticorps TNFRSF1A, anticorps Tnfrsf1a, anticorps tnfrsf1a.S, anticorps tnfrsf1a, anticorps TNF
Sujet
TNF Receptor I contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein), and subsequent interactions with FADD. TNF Receptor I can also activate the transcription factor NFkB via TRAF2 (TNF Receptor associated factor 2). The cytoplasmic domain of TNF Receptor I can directly interact with Jak kinase, thereby activating the JAK/STAT signal transduction cascade. TNF Receptor I is expressed by virtually all nucleated mammalian cells, including hepatocytes, monocytes and neutrophils, cardiac muscle cells, endothelial cells, and CD34 + hematopoietic progenitors. Both TNF alpha and TNF beta bind to TNF Receptor I.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Poids moléculaire
50.5 kDa (NP_001056.1)
Pathways
Signalisation NF-kappaB , Apoptose , Caspase Cascade in Apoptosis , Hepatitis C , Ubiquitin Proteasome Pathway
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