C5 anticorps

N° du produit ABIN1106791

Détail du produit anti-C5 anticorps

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein G

Clone: 2952

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % bovine serum albumin

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: Complement C5 (C5 Produits)

Synonymes: anticorps C5, anticorps LOC565774, anticorps C5a, anticorps C5b, anticorps CPAMD4, anticorps Hc, anticorps RGD1561905, anticorps He, anticorps complement C5, anticorps complement component 5, anticorps hemolytic complement, anticorps C5, anticorps c5, anticorps Hc

Sujet: C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5. C5a induces smooth muscle contraction, increases vascular permeability, causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Recent studies indicate the modulation of the acute-phase response in liver and an overall immune response by inducing synthesis of cytokines such as TNF-alpha IL-1beta, IL-6 and IL-8.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CPAMD4, Complement component 5

ID gène: 9606

UniProt: P01031

Pathways: Système du Complément, Carbohydrate Homeostasis