BMPR2
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Western Blot (1:100-500), Immunohistochemistry, IHC (1:100-500), Immunocytochemistry, ICC (1:100-500). Other applications have not been tested. The optimal dilutions should be determined by end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Agent conservateur
Sodium azide, Thimerosal (Merthiolate)
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Date de péremption
12 months
Antigène
BMPR2
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
Autre désignation
Bone morphogenetic protein receptor type II, BMPR2 (BMPR2 Produits)
Synonymes
anticorps BMPR-II, anticorps BMPR3, anticorps BMR2, anticorps BRK-3, anticorps PPH1, anticorps T-ALK, anticorps 2610024H22Rik, anticorps AL117858, anticorps AW546137, anticorps BB189135, anticorps BMP-2, anticorps BMPR-2, anticorps BMPRII, anticorps Gm20272, anticorps Bmpr-II, anticorps bmprii, anticorps bone morphogenetic protein receptor type 2, anticorps bone morphogenetic protein receptor, type II b (serine/threonine kinase), anticorps bone morphogenetic protein receptor, type II (serine/threonine kinase), anticorps BMPR2, anticorps bmpr2b, anticorps Bmpr2
Sujet
Bone morphogenetic protein receptor type II, BMPR2 is a serine/threonine receptor kinase. It binds bone morphogenetic proteins, members of the TGF beta superfamily of ligands. BMPs are involved in a host of cellular functions including osteogenesis, cell growth and cell differentiation. Unlike the TGF beta type II receptor, which has a high affinity for TGF- beta1, BMPR2 does not have a high affinity for BMP-2, BMP-7 and BMP-4, unless it is co-expressed with a type I BMP receptor. 1 The low affinity for ligands suggests that BMPR2 may differ in the from other type II TGF beta receptors in that the ligand may bind the type I receptor first. 2