CD47 anticorps

N° du produit ABIN1177375

Détail du produit anti-CD47 anticorps

Antigène: CD47

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD47 est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone: B6H12

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-CD47 (ABIN1177375)

Lindberg, Lublin, Telen, Veile, Miller, Donis-Keller, Brown: "Rh-related antigen CD47 is the signal-transducer integrin-associated protein." dans: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).

Brown, Hooper, Ho, Gresham: "Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins." dans: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2785-94, (1991) (PubMed).

Détails sur CD47

Antigène: CD47

Autre désignation: CD47 (IAP) (CD47 Produits)

Synonymes: anticorps IAP, anticorps MER6, anticorps OA3, anticorps 9130415E20Rik, anticorps AA407862, anticorps AI848868, anticorps AW108519, anticorps B430305P08Rik, anticorps Itgp, anticorps CD47/IAP, anticorps alkaline phosphatase, intestinal, anticorps CD47 molecule, anticorps CD47 antigen (Rh-related antigen, integrin-associated signal transducer), anticorps Cd47 molecule, anticorps ALPI, anticorps CD47, anticorps Cd47

Sujet: The B6H12 monoclonal antibody specifically binds to a 42-52 kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. The B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells.
Synonyms: IAP, CDw149, gp42, MER6, Neurophilin, OA3 , Rh-related antigen