Integrin Alpha2b anticorps (FITC)

N° du produit ABIN119841

Détail du produit anti-Integrin Alpha2b anticorps (FITC)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises the integrin alpha IIb subunit CD41.

Purification: Protein G affinity chromatography

Clone: MWReg30

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo . We recommend the use of ABIN119839 for use in functional studies.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide and 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Integrin Alpha2b (FITC) (ABIN119841)

Zanzinger, Schellack, Nausch, Cerwenka: "Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytes." dans: Immunology, Vol. 128, Issue 2, pp. 185-95, (2009) (PubMed).

Larson, Watson: "Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3." dans: Blood, Vol. 108, Issue 5, pp. 1509-14, (2006) (PubMed).

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41 / ITGA2B (CD41 Produits)

Synonymes: anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B

Sujet: CD41 is expressed on platelets and megakaryocytes and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

ID gène: 16399

NCBI Accession: NP_034705

UniProt: Q9QUM0

Pathways: Integrin Complex