CD59 anticorps
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- Antigène Voir toutes CD59 Anticorps
- CD59
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Reactivité
- Humain, Porc
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD59 est non-conjugé
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificité
- The antibody MEM-129 reacts with CD59 (Protectin).
- Purification
- Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
- Pureté
- > 95 % (by SDS-PAGE).
- Immunogène
- Human peripheral blood lymphocytes
- Clone
- MEM-129
- Isotype
- IgM
- Top Product
- Discover our top product CD59 Anticorps primaire
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- Indications d'application
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Flow Cytometry. Functional Studies (The antibody activates T-cells).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
- Agent conservateur
- Azide free
- Stock
- 4 °C
- Stockage commentaire
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Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- CD59
- Autre désignation
- CD59 (CD59 Produits)
- Synonymes
- anticorps 16.3A5, anticorps 1F5, anticorps EJ16, anticorps EJ30, anticorps EL32, anticorps G344, anticorps HRF-20, anticorps HRF20, anticorps MAC-IP, anticorps MACIF, anticorps MEM43, anticorps MIC11, anticorps MIN1, anticorps MIN2, anticorps MIN3, anticorps MIRL, anticorps MSK21, anticorps p18-20, anticorps Cd59a, anticorps Cd59b, anticorps MACIP, anticorps CD59 molecule (CD59 blood group), anticorps CD59 molecule, anticorps CD59, anticorps Cd59
- Sujet
- CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
- ID gène
- 966
- UniProt
- P13987
- Pathways
- Système du Complément
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