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CD59 anticorps

CD59 Reactivité: Humain, Porc FACS, Func Hôte: Souris Monoclonal MEM-129 unconjugated
N° du produit ABIN120694
  • Antigène Voir toutes CD59 Anticorps
    CD59
    Reactivité
    • 135
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Humain, Porc
    Hôte
    • 88
    • 68
    • 6
    • 4
    Souris
    Clonalité
    • 94
    • 69
    • 1
    Monoclonal
    Conjugué
    • 77
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD59 est non-conjugé
    Application
    • 98
    • 69
    • 46
    • 40
    • 31
    • 26
    • 25
    • 15
    • 14
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Specificité
    The antibody MEM-129 reacts with CD59 (Protectin).
    Purification
    Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
    Pureté
    > 95 % (by SDS-PAGE).
    Immunogène
    Human peripheral blood lymphocytes
    Clone
    MEM-129
    Isotype
    IgM
    Top Product
    Discover our top product CD59 Anticorps primaire
  • Indications d'application
    Flow Cytometry. Functional Studies (The antibody activates T-cells).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
    Agent conservateur
    Azide free
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf Life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    CD59
    Autre désignation
    CD59 (CD59 Produits)
    Synonymes
    anticorps 16.3A5, anticorps 1F5, anticorps EJ16, anticorps EJ30, anticorps EL32, anticorps G344, anticorps HRF-20, anticorps HRF20, anticorps MAC-IP, anticorps MACIF, anticorps MEM43, anticorps MIC11, anticorps MIN1, anticorps MIN2, anticorps MIN3, anticorps MIRL, anticorps MSK21, anticorps p18-20, anticorps Cd59a, anticorps Cd59b, anticorps MACIP, anticorps CD59 molecule (CD59 blood group), anticorps CD59 molecule, anticorps CD59, anticorps Cd59
    Sujet
    CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
    ID gène
    966
    UniProt
    P13987
    Pathways
    Système du Complément
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