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FLIP anticorps (C-Term, long form)

CFLAR Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN126994
  • Antigène Voir toutes FLIP (CFLAR) Anticorps
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Épitope
    • 16
    • 15
    • 15
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, long form
    Reactivité
    • 94
    • 66
    • 57
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 84
    • 14
    • 2
    Lapin
    Clonalité
    • 86
    • 14
    Polyclonal
    Conjugué
    • 52
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp FLIP est non-conjugé
    Application
    • 95
    • 39
    • 26
    • 26
    • 21
    • 20
    • 14
    • 12
    • 12
    • 10
    • 8
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    The immunoaffinity-purified antibody detects 58 kDa FLIPL on SDS-PAGE immunoblots, in samples from human, mouse and rat origins. The antibody recognizes only the FLIPL form.
    Purification
    Affinity purified
    Immunogène
    Synthetic peptide near the C-terminus of human FLIPalpha/FLIPL form.
    Top Product
    Discover our top product CFLAR Anticorps primaire
  • Indications d'application
    Western Blot: 0.5-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thymerosal
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Antigène
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Autre désignation
    CFLAR / Casper / I-FLICE (CFLAR Produits)
    Synonymes
    anticorps Clarp1, anticorps cflar, anticorps CFLAR, anticorps FLIP, anticorps CASH, anticorps CASP8AP1, anticorps CLARP, anticorps Casper, anticorps FLAME, anticorps FLAME-1, anticorps FLAME1, anticorps I-FLICE, anticorps MRIT, anticorps c-FLIP, anticorps c-FLIPL, anticorps c-FLIPR, anticorps c-FLIPS, anticorps 2310024N18Rik, anticorps A430105C05Rik, anticorps Cash, anticorps ENSMUSG00000072980, anticorps Flip, anticorps Gm9845, anticorps c-Flip, anticorps CASP8 and FADD-like apoptosis regulator a, anticorps CASP8 and FADD like apoptosis regulator, anticorps CASP8 and FADD like apoptosis regulator S homeolog, anticorps CASP8 and FADD-like apoptosis regulator, anticorps cflara, anticorps CFLAR, anticorps cflar, anticorps cflar.S, anticorps Cflar
    Sujet
    Caspase-8 (FLICE) and -10 (FLICE2) are two pivotal members in the caspase family. Human and viral FLICE-inhibitory proteins were designated as v-FLIPs and c-FLIP, respectively. c-FLIP was cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH AND CLARP. c-FLIP contains two death effector domains and has sequence homology to caspase-8. c-FLIP interacts with adapter protein FADD and caspaser-8 and -10, and potently inhibits apoptosis induced by all known death receptors. Two splice variants of c-FLIP have been identified and termed FLIPL and FLIPs. The mRNA for c-FLIP is predominantly expressed in muscle and lymphoid tissue.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
    ID gène
    8837
    NCBI Accession
    NP_001120655
    UniProt
    O15519
    Pathways
    Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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