alpha Adaptin anticorps (AA 3-14)

N° du produit ABIN129553

Détail du produit anti-alpha Adaptin anticorps

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Épitope: AA 3-14

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Adaptin est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Chimpanzé, Orang-Utan, Souris, Rat (Rattus), Poulet, Chien

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 3-14 of Human AP2A1 and AP2A2 proteins.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 104-107 kDa in size corresponding to AP2A1 or AP2A2 proteins by western blotting in the appropriate cell lysate or extract. Multiple isoforms of each subunit exist for these proteins. The immunogen sequence is found in both AP2A1 and AP2A2. This antibody recognizes a band of approximately 100 kDa in multiple human cell lines and specific reactivity can be blocked with the immunizing peptide.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.7 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur alpha Adaptin

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Autre désignation: AP2A (AP2A1 Produits)

Synonymes: anticorps ADTAA, anticorps AP2-ALPHA, anticorps CLAPA1, anticorps adtaa, anticorps clapa1, anticorps ap2-alpha, anticorps AP2A1, anticorps Adtaa, anticorps adaptor related protein complex 2 alpha 1 subunit, anticorps adaptor-related protein complex 2, alpha 1 subunit, anticorps AP-2 complex subunit alpha-1, anticorps AP2A1, anticorps ap2a1, anticorps Ap2a1, anticorps EDI_093420, anticorps EDI_259990

Sujet: The AP2A1 and AP2A2 represent the AP2 alpha proteins that are found in the AP2 complex in clathrin-coated vesicles. AP2A is also known as Alpha-adaptin A, Adaptor protein complex AP-2 alpha-1 subunit, Clathrin assembly protein complex 2 alpha-A large chain, 100 kDa coated vesicle protein A and Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit.  The AP2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles, which link clathrin to receptors in vesicles.
Synonyms: AP-2 complex subunit alpha-1, Adapter-related protein complex 2 alpha-1 subunit, Adaptor protein complex AP-2 subunit alpha-1 Alpha1-adaptin, Plasma membrane adaptor HA2/AP2 Clathrin assembly protein complex 2 alpha-A large chain

ID gène: 161, 27477041

NCBI Accession: NP_036437

UniProt: O95782

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation