FANCC anticorps (AA 96-112)

N° du produit ABIN129608

Détail du produit anti-FANCC anticorps

Antigène: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Épitope: AA 96-112

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCC est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Chimpanzé

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 96-112 of Human FANCC.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.45 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur FANCC

Antigène: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Autre désignation: FANCC (FANCC Produits)

Synonymes: anticorps zgc:154105, anticorps FANCC, anticorps fa3, anticorps fac, anticorps facc, anticorps FA3, anticorps FAC, anticorps FACC, anticorps BB116513, anticorps Facc, anticorps Fanconi anemia complementation group C, anticorps Fanconi anemia, complementation group C, anticorps Fanconi anemia complementation group C L homeolog, anticorps FANCC, anticorps fancc, anticorps fancc.L, anticorps Fancc

Sujet: FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.  FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.  FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is ubiquitously expressed.  Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and
Synonyms: bA80I15.1 antibody, FA 3 antibody, FA3 antibody, FAC antibody, FACC antibody, Fanconi anemia complementation group C antibody

ID gène: 2176, 56118236

UniProt: Q00597

Pathways: Réparation de l'ADN