c-MET anticorps
-
- Antigène Voir toutes c-MET (MET) Anticorps
- c-MET (MET) (Met Proto-Oncogene (MET))
-
Reactivité
- Humain
-
Hôte
- Rat
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp c-MET est non-conjugé
-
Application
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Specificité
- Anti-human c-Met
- Attributs du produit
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Purification
- Protein G
- Immunogène
- genetic immunisation with cDNA encoding human c-Met
- Clone
- BCI-3E7
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product MET Anticorps primaire
-
-
- Indications d'application
-
Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Restrictions
- For Research Use only
-
- Buffer
- PBS, pH 7.2
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C
- Stockage commentaire
- short term: 2 °C - 8 °C, long term: -20 °C
-
- Antigène
- c-MET (MET) (Met Proto-Oncogene (MET))
- Autre désignation
- c-Met (MET Produits)
- Synonymes
- anticorps AUTS9, anticorps HGFR, anticorps RCCP2, anticorps c-Met, anticorps AI838057, anticorps HGF, anticorps Par4, anticorps Hgfr, anticorps c-met, anticorps MET, anticorps C-MET, anticorps met, anticorps met-A, anticorps MET proto-oncogene, receptor tyrosine kinase, anticorps met proto-oncogene, anticorps MET proto-oncogene, receptor tyrosine kinase L homeolog, anticorps MET, anticorps Met, anticorps met.L
- Sujet
- C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
- UniProt
- P08581
- Pathways
- Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
-