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c-MET anticorps

MET Reactivité: Humain FACS, cELISA Hôte: Rat Monoclonal BCI-3E7 unconjugated
N° du produit ABIN1381745
  • Antigène Voir toutes c-MET (MET) Anticorps
    c-MET (MET) (Met Proto-Oncogene (MET))
    Reactivité
    • 250
    • 144
    • 98
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 222
    • 39
    • 3
    • 1
    Rat
    Clonalité
    • 210
    • 55
    Monoclonal
    Conjugué
    • 131
    • 20
    • 13
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp c-MET est non-conjugé
    Application
    • 182
    • 105
    • 50
    • 43
    • 31
    • 27
    • 26
    • 24
    • 15
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Specificité
    Anti-human c-Met
    Attributs du produit
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Purification
    Protein G
    Immunogène
    genetic immunisation with cDNA encoding human c-Met
    Clone
    BCI-3E7
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product MET Anticorps primaire
  • Indications d'application
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C
    Stockage commentaire
    short term: 2 °C - 8 °C, long term: -20 °C
  • Antigène
    c-MET (MET) (Met Proto-Oncogene (MET))
    Autre désignation
    c-Met (MET Produits)
    Synonymes
    anticorps AUTS9, anticorps HGFR, anticorps RCCP2, anticorps c-Met, anticorps AI838057, anticorps HGF, anticorps Par4, anticorps Hgfr, anticorps c-met, anticorps MET, anticorps C-MET, anticorps met, anticorps met-A, anticorps MET proto-oncogene, receptor tyrosine kinase, anticorps met proto-oncogene, anticorps MET proto-oncogene, receptor tyrosine kinase L homeolog, anticorps MET, anticorps Met, anticorps met.L
    Sujet
    C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
    UniProt
    P08581
    Pathways
    Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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