LIG4 anticorps (AA 51-150) (Alexa Fluor 647)

N° du produit ABIN1396061

Détail du produit anti-LIG4 anticorps (Alexa Fluor 647)

Antigène: LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

Épitope: AA 51-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIG4 est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DNA Ligase IV

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur LIG4

Antigène: LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

Autre désignation: DNA Ligase IV/LIG4 (LIG4 Produits)

Synonymes: anticorps zgc:165595, anticorps lig4, anticorps DNA LIGASE IV, anticorps LIG4, anticorps lig4-A, anticorps 5830471N16Rik, anticorps tiny, anticorps DNL4, anticorps ligase IV, DNA, ATP-dependent, anticorps DNA ligase 4, anticorps ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining, anticorps DNA ligase IV, anticorps ligase IV, DNA, ATP-dependent L homeolog, anticorps lig4, anticorps LIG4, anticorps LOC100212302, anticorps CpipJ_CPIJ005161, anticorps PTRG_09982, anticorps MCYG_05151, anticorps LOC657210, anticorps ATLIG4, anticorps lig4.L, anticorps Lig4

Sujet:

Synonyms: LIG4S, DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4

Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

ID gène: 3981

UniProt: P49917

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response