RIC8A anticorps (AA 244-272)

N° du produit ABIN1538170

Détail du produit anti-RIC8A anticorps

Antigène: RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Épitope: AA 244-272

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIC8A est non-conjugé

Application: Western Blotting (WB)

Homologie: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RIC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-272 amino acids from the Central region of human RIC8A.

Clone: RB37066

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RIC8A Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur RIC8A

Antigène: RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Autre désignation: RIC8A (RIC8A Produits)

Synonymes: anticorps RIC8, anticorps AI114950, anticorps RIC-8, anticorps Ric8a, anticorps Ric-8A, anticorps Ric8, anticorps ric-8, anticorps ric8, anticorps synembryn, anticorps xtric-8, anticorps zgc:92294, anticorps Syn, anticorps ric8a, anticorps ric8ab, anticorps CG15797, anticorps DmRic8, anticorps Dmel\\CG15797, anticorps Ric-8, anticorps l(1)G0397, anticorps ric-8a, anticorps ricc8aa, anticorps fj97c10, anticorps synbl, anticorps wu:fj97c10, anticorps RIC8 guanine nucleotide exchange factor A, anticorps microRNA 6743, anticorps synembryn-A, anticorps RIC8 guanine nucleotide exchange factor A L homeolog, anticorps CG15797 gene product from transcript CG15797-RB, anticorps synembryn, anticorps RIC8 guanine nucleotide exchange factor A S homeolog, anticorps Synembryn, anticorps RIC8 guanine nucleotide exchange factor B, anticorps RIC8A, anticorps Ric8a, anticorps ric8a, anticorps MIR6743, anticorps Tsp_08768, anticorps ric8a.L, anticorps LOC411841, anticorps ric8a.S, anticorps ric-8, anticorps ric8b

Sujet: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Poids moléculaire: 59710

ID gène: 60626

NCBI Accession: NP_068751

UniProt: Q9NPQ8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization