RIC8A anticorps (AA 362-531)

N° du produit ABIN7171203

Détail du produit anti-RIC8A anticorps

Antigène: RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Épitope: AA 362-531

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIC8A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Synembryn-A protein (362-531AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RIC8A

Antigène: RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Autre désignation: RIC8A (RIC8A Produits)

Synonymes: anticorps RIC8, anticorps AI114950, anticorps RIC-8, anticorps Ric8a, anticorps Ric-8A, anticorps Ric8, anticorps ric-8, anticorps ric8, anticorps synembryn, anticorps xtric-8, anticorps zgc:92294, anticorps Syn, anticorps ric8a, anticorps ric8ab, anticorps CG15797, anticorps DmRic8, anticorps Dmel\\CG15797, anticorps Ric-8, anticorps l(1)G0397, anticorps ric-8a, anticorps ricc8aa, anticorps fj97c10, anticorps synbl, anticorps wu:fj97c10, anticorps RIC8 guanine nucleotide exchange factor A, anticorps microRNA 6743, anticorps synembryn-A, anticorps RIC8 guanine nucleotide exchange factor A L homeolog, anticorps CG15797 gene product from transcript CG15797-RB, anticorps synembryn, anticorps RIC8 guanine nucleotide exchange factor A S homeolog, anticorps Synembryn, anticorps RIC8 guanine nucleotide exchange factor B, anticorps RIC8A, anticorps Ric8a, anticorps ric8a, anticorps MIR6743, anticorps Tsp_08768, anticorps ric8a.L, anticorps LOC411841, anticorps ric8a.S, anticorps ric-8, anticorps ric8b

Sujet:

Background: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Aliases: MGC104517 antibody, MGC131931 antibody, MGC148073 antibody, MGC148074 antibody, Protein Ric-8A antibody, resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody, RIC8 antibody, RIC8A antibody, RIC8A_HUMAN antibody, Synembryn-A antibody

UniProt: Q9NPQ8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization