RIC8A anticorps (C-Term)
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- Antigène Voir toutes RIC8A Anticorps
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RIC8A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Rat (Rattus), Boeuf (Vache)
- Réactivité croisée (Details)
- Rat (100 %), Bovine (100 %)
- Attributs du produit
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Rabbit Polyclonal antibody to RIC8A (resistance to inhibitors of cholinesterase 8 homolog A (C. elegans))
RIC8A antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RIC8A. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product RIC8A Anticorps primaire
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- Indications d'application
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Commentaires
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Positive Control: A431 , H1299 , HeLa , HepG2 , Raji
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.85 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
- Autre désignation
- RIC8A (RIC8A Produits)
- Synonymes
- anticorps RIC8, anticorps AI114950, anticorps RIC-8, anticorps Ric8a, anticorps Ric-8A, anticorps Ric8, anticorps ric-8, anticorps ric8, anticorps synembryn, anticorps xtric-8, anticorps zgc:92294, anticorps Syn, anticorps ric8a, anticorps ric8ab, anticorps CG15797, anticorps DmRic8, anticorps Dmel\\CG15797, anticorps Ric-8, anticorps l(1)G0397, anticorps ric-8a, anticorps ricc8aa, anticorps fj97c10, anticorps synbl, anticorps wu:fj97c10, anticorps RIC8 guanine nucleotide exchange factor A, anticorps microRNA 6743, anticorps synembryn-A, anticorps RIC8 guanine nucleotide exchange factor A L homeolog, anticorps CG15797 gene product from transcript CG15797-RB, anticorps synembryn, anticorps RIC8 guanine nucleotide exchange factor A S homeolog, anticorps Synembryn, anticorps RIC8 guanine nucleotide exchange factor B, anticorps RIC8A, anticorps Ric8a, anticorps ric8a, anticorps MIR6743, anticorps Tsp_08768, anticorps ric8a.L, anticorps LOC411841, anticorps ric8a.S, anticorps ric-8, anticorps ric8b
- Sujet
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Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
- Poids moléculaire
- 60 kDa
- ID gène
- 60626
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
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