CD247 anticorps

N° du produit ABIN161386

Détail du produit anti-CD247 anticorps

Antigène: CD247 (CD247 Molecule (CD247))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD247 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Specificité: Mouse CD3z (zeta chain) also known as CD247

Purification: Purified

Immunogène: KLH conjugated mouse zeta-chain (CD3) sequence 151-164 . Donor: Armenian hamster

Clone: H146-968

Isotype: IgG

Information d'application

Indications d'application: This clone (H146-968) has been reported to work in flow cytometry (in permeabilized cells), Western Blotting and ELISA.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/ml

Stock: 4 °C

Détails sur CD247

Antigène: CD247 (CD247 Molecule (CD247))

Autre désignation: CD3z (CD247 Produits)

Synonymes: anticorps CD3-ZETA, anticorps CD3H, anticorps CD3Q, anticorps CD3Z, anticorps T3Z, anticorps TCRZ, anticorps 4930549J05Rik, anticorps A430104F18Rik, anticorps AW552088, anticorps Cd3, anticorps Cd3-eta, anticorps Cd3-zeta, anticorps Cd3h, anticorps Cd3z, anticorps Cd3zeta, anticorps T3z, anticorps Tcrk, anticorps Tcrz, anticorps LOC100136514, anticorps LOC100136549, anticorps LOC100305023, anticorps CD247, anticorps TCRzeta, anticorps CD247 molecule, anticorps CD247 antigen, anticorps CD3zeta-2, anticorps CD3zeta-1, anticorps Cd247 molecule, anticorps CD247, anticorps Cd247, anticorps cd3z, anticorps cd247

Sujet: Purified Anti-Mouse CD3z Monoclonal Antibody detects the zeta subunit of the T cell receptor (TCR). The TCR complex consists of a ligand specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma, delta, eta and zeta subunits. This complex regulates assembly and expression of the receptor and is thought to be responsible for transmembrane transduction of signals after binding to TCR Studies have suggested that the CD3z subunit (also know as CD247) plays an important role in two distinct cellular compartments. In the cytoplasm, it may function to regulate Ag receptor expression and in the plasma membrane it may be required for optimal signaling by the physiologic ligand Ag/MHC. The CD3z subunit is also associated with the CD16 IgG Fc receptor on NK cells. This clone (H146-968) has been reported to work in flow cytometry (in permeabilized cells), Western Blotting and ELISA.

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway