HSP27 anticorps
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- Antigène Voir toutes HSP27 (HSPB1) Anticorps
- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HSP27 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
- Immunogène
- Recombinant Hsp27, Accession / GI number: NP_001531
- Clone
- 2A5
- Isotype
- Kappa
- Top Product
- Discover our top product HSPB1 Anticorps primaire
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- Indications d'application
- Recommended dilution 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml
- Buffer
- In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
- Autre désignation
- Hsp27 (HSPB1 Produits)
- Synonymes
- anticorps CMT2F, anticorps HMN2B, anticorps HS.76067, anticorps HSP27, anticorps HSP28, anticorps Hsp25, anticorps SRP27, anticorps 27kDa, anticorps Hsp27, anticorps cb153, anticorps cb660, anticorps hsp1, anticorps hsp25, anticorps hsp27, anticorps id:ibd2821, anticorps sb:cb660, anticorps zgc:103437, anticorps HSPB1, anticorps cmt2f, anticorps hs.76067, anticorps hsp28, anticorps heat shock protein family B (small) member 1, anticorps heat shock protein 1, anticorps heat shock protein, alpha-crystallin-related, 1, anticorps heat shock protein family B (small) member 1 L homeolog, anticorps HSPB1, anticorps Hspb1, anticorps hspb1, anticorps hspb1.L
- Sujet
- Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.
- Pathways
- Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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