MGMT anticorps (AA 1-207)
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- Antigène Voir toutes MGMT Anticorps
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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Épitope
- AA 1-207
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MGMT est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEFP VPALHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN
- Réactivité croisée
- Humain, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human MGMT (XP_005252739.1).
- Isotype
- IgG
- Top Product
- Discover our top product MGMT Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Autre désignation
- MGMT (MGMT Produits)
- Synonymes
- anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt
- Sujet
- Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.,MGMT,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MGMT
- Poids moléculaire
- 21 kDa
- ID gène
- 4255
- UniProt
- P16455
- Pathways
- Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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