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ZFAND5 anticorps (AA 121-213) (HRP)

ZFAND5 Reactivité: Humain IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711840
  • Antigène Voir toutes ZFAND5 Anticorps
    ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
    Épitope
    • 14
    • 1
    • 1
    • 1
    AA 121-213
    Reactivité
    • 20
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 18
    • 2
    Lapin
    Clonalité
    • 18
    • 2
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZFAND5 est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ZFAND5
    Isotype
    IgG
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
    Autre désignation
    ZFAND5 (ZFAND5 Produits)
    Synonymes
    anticorps 2310057A04Rik, anticorps 5830475F03Rik, anticorps AA415485, anticorps Za20d2, anticorps Zfp216, anticorps ZA20D2, anticorps ZFAND5A, anticorps ZNF216, anticorps wu:fi29f06, anticorps za20d2l, anticorps zgc:56057, anticorps za20d2, anticorps zfand5, anticorps zfand5-a, anticorps zfand5-b, anticorps zfand5a, anticorps znf216, anticorps id:ibd2892, anticorps wu:fb16d02, anticorps wu:fc67h07, anticorps zgc:73363, anticorps zinc finger, AN1-type domain 5, anticorps zinc finger AN1-type containing 5, anticorps zinc finger, AN1-type domain 5b, anticorps zinc finger AN1-type containing 5 L homeolog, anticorps zinc finger, AN1-type domain 5a, anticorps Zfand5, anticorps ZFAND5, anticorps zfand5b, anticorps zfand5.L, anticorps zfand5a
    Sujet

    Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

    Subcellular location: Cytoplasm

    Synonyms: ZA20D2, ZNF216, ZFAND5A, AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216, ZFAND5

    ID gène
    7763
    UniProt
    O76080
    Pathways
    Platelet-derived growth Factor Receptor Signaling
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