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Prostaglandin D2 Receptor 2 (PTGDR2) (AA 121-220) anticorps

PTGDR2 Reactivité: Humain WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713826
  • Antigène Voir toutes Prostaglandin D2 Receptor 2 (PTGDR2) Anticorps
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Épitope
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reactivité
    • 65
    • 24
    • 13
    • 4
    • 3
    Humain
    Hôte
    • 52
    • 13
    • 1
    Lapin
    Clonalité
    • 52
    • 14
    Polyclonal
    Conjugué
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 17
    • 15
    • 12
    • 12
    • 12
    • 11
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GPR44/CD294
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Autre désignation
    GPR44 (PTGDR2 Produits)
    Synonymes
    anticorps CD294, anticorps CRTH2, anticorps DL1R, anticorps DP2, anticorps GPR44, anticorps Crth2, anticorps Grp45, anticorps Ptgdr2, anticorps Gpr44, anticorps prostaglandin D2 receptor 2, anticorps PTGDR2, anticorps Ptgdr2
    Sujet

    Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

    Subcellular location: Cell membrane

    Synonyms: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44, PTGDR2

    ID gène
    11251
    UniProt
    Q9Y5Y4
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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