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TNFRSF1A anticorps
TNFRSF1A
Reactivité: Humain
IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN1875131
Détail du produit anti-TNFRSF1A anticorps
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Antigène
Voir toutes TNFRSF1A Anticorps
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Reactivité
Toutes les réactivités sur TNFRSF1A Anticorps
Humain
Hôte
Toutes les hôtes sur TNFRSF1A Anticorps
Lapin
Clonalité
Toutes les clonalités sur TNFRSF1A Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers TNFRSF1A Anticorps
Cet anticorp TNFRSF1A est non-conjugé
Application
Tous les applications à travers TNFRSF1A Anticorps.
Immunofluorescence (IF)
Attributs du produit
Expected molecular weight of target: 455 kDa
Purification
Affinity purification
Immunogène
Recombinant protein of human TNFRSF1A
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
IF 1:50 - 1:200
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20°C.
Détails sur TNFRSF1A
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Antigène
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Autre désignation
TNF-R1 (TNFRSF1A Produits )
Synonymes
anticorps CD120a, anticorps FPF, anticorps MS5, anticorps TBP1, anticorps TNF-R, anticorps TNF-R-I, anticorps TNF-R55, anticorps TNFAR, anticorps TNFR1, anticorps TNFR1-d2, anticorps TNFR55, anticorps TNFR60, anticorps p55, anticorps p55-R, anticorps p60, anticorps TNF-R1, anticorps TNF-alphaR1, anticorps TNFRI, anticorps TNFRp55, anticorps TNFalpha-R1, anticorps Tnfr-2, anticorps Tnfr1, anticorps fpf, anticorps tbp1, anticorps p55-r, anticorps tnf-r, anticorps tnfar, anticorps tnfr1, anticorps cd120a, anticorps tnfr55, anticorps tnfr60, anticorps xtnfr1, anticorps wu:fj65b10, anticorps zgc:85914, anticorps TNFR I, anticorps TNFRSF1A, anticorps TNFA, anticorps cTNF, anticorps TNF receptor superfamily member 1A, anticorps tumor necrosis factor receptor superfamily, member 1a, anticorps TNF receptor superfamily member 1A S homeolog, anticorps tumor necrosis factor, anticorps TNFRSF1A, anticorps Tnfrsf1a, anticorps tnfrsf1a.S, anticorps tnfrsf1a, anticorps TNF
Sujet
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
Poids moléculaire
50.495 kDa
ID gène
7132
UniProt
P19438
Pathways
Signalisation NF-kappaB , Apoptose , Caspase Cascade in Apoptosis , Hepatitis C , Ubiquitin Proteasome Pathway
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