PCSK5 anticorps (AA 601-913)

N° du produit ABIN6145326

Détail du produit anti-PCSK5 anticorps

Antigène: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Épitope: AA 601-913

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK5 est non-conjugé

Application: Western Blotting (WB)

Séquence: QPYSPTNEFP KVERFRYSRV EDPTDDYGTE DYAGPCDPEC SEVGCDGPGP DHCNDCLHYY YKLKNNTRIC VSSCPPGHYH ADKKRCRKCA PNCESCFGSH GDQCMSCKYG YFLNEETNSC VTHCPDGSYQ DTKKNLCRKC SENCKTCTEF HNCTECRDGL SLQGSRCSVS CEDGRYFNGQ DCQPCHRFCA TCAGAGADGC INCTEGYFME DGRCVQSCSI SYYFDHSSEN GYKSCKKCDI SCLTCNGPGF KNCTSCPSGY LLDLGMCQMG AICKDATEES WAEGGFCMLV KKNNLCQRKV LQQLCCKTCT FQG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 601-913 of human PCSK5 (NP_006191.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PCSK5

Antigène: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Autre désignation: PCSK5 (PCSK5 Produits)

Synonymes: anticorps PC5, anticorps PC6, anticorps PC6A, anticorps SPC6, anticorps subtilase, anticorps PC5/6A, anticorps PC5A, anticorps b2b1549Clo, anticorps b2b585Clo, anticorps Pc5, anticorps fur2, anticorps spc6, anticorps spc6A, anticorps MGC98915, anticorps PCSK5, anticorps pc6, anticorps spc6a, anticorps pcsk5, anticorps zgc:165659, anticorps proprotein convertase subtilisin/kexin type 5, anticorps proprotein convertase subtilisin/kexin type 5 S homeolog, anticorps proprotein convertase subtilisin/kexin type 5b, anticorps PCSK5, anticorps Pcsk5, anticorps pcsk5.S, anticorps LOC528098, anticorps pcsk5, anticorps pcsk5b

Sujet: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).,PCSK5,PC5,PC6,PC6A,SPC6,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,PCSK5

Poids moléculaire: 101 kDa/206 kDa

ID gène: 5125

UniProt: Q92824

Pathways: Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones