Caspase 8 anticorps (C-Term)
-
- Antigène Voir toutes Caspase 8 (CASP8) Anticorps
- Caspase 8 (CASP8)
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Caspase 8 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 15 amino acid peptide from near the carboxy terminus human caspase-8 isoform E.
- Top Product
- Discover our top product CASP8 Anticorps primaire
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
-
- Antigène
- Caspase 8 (CASP8)
- Autre désignation
- Caspase-8 (CASP8 Produits)
- Synonymes
- anticorps casp8-A, anticorps xCaspase-8, anticorps casp8, anticorps CASP8, anticorps CASP-8, anticorps FLICE, anticorps MACH, anticorps Mch5, anticorps ALPS2B, anticorps CAP4, anticorps Casp-8, anticorps MCH5, anticorps caspase-8, anticorps zgc:92075, anticorps caspase 8 L homeolog, anticorps death related ced-3/Nedd2-like protein, anticorps caspase 8, anticorps caspase-8, anticorps caspase-8-like, anticorps caspase 8, apoptosis-related cysteine peptidase, anticorps casp8.L, anticorps LOC661095, anticorps CASP8, anticorps LOC5563818, anticorps casp8, anticorps LOC100222284, anticorps Casp8
- Sujet
-
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies.Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens.The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death.Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex.The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation.FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis.This antibody will only detect isoform E of caspase-8.
Synonyms: FLICE, MACH, Mch5 - NCBI Accession
- NP_001219
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
-