FNIP2 anticorps (C-Term)

N° du produit ABIN1887136

Détail du produit anti-FNIP2 anticorps

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNIP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the carboxy terminus of human FNIP2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur FNIP2

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Autre désignation: FNIP2 (FNIP2 Produits)

Synonymes: anticorps LOC797213, anticorps FNIPL, anticorps MAPO1, anticorps D630023B12Rik, anticorps mKIAA1450, anticorps RGD1562174, anticorps folliculin interacting protein 2, anticorps si:ch211-42i9.8, anticorps FNIP2, anticorps si:ch211-42i9.8, anticorps fnip2, anticorps Fnip2

Sujet: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene.Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors.Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation.FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
Synonyms: Folliculin interacting protein 2, FNIPL

NCBI Accession: NP_065891