SLC39A3
Reactivité: Humain, Souris
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
PE
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
SLC39A3
(Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))
anticorps AI845814, anticorps Zip3, anticorps ZIP3, anticorps wu:fc84e09, anticorps zgc:158334, anticorps solute carrier family 39 (zinc transporter), member 3, anticorps solute carrier family 39 member 3, anticorps Slc39a3, anticorps slc39a3, anticorps SLC39A3
Sujet
The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice.Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient.More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment. Synonyms: Solute carrier family 39 member A3, Slc39A3