MGMT anticorps (AA 4-207) (HRP)

N° du produit ABIN1993154

Détail du produit anti-MGMT anticorps (HRP)

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Épitope: AA 4-207

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGMT est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Methylated-DNA--protein-cysteine methyltransferase protein (4-207AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MGMT

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Autre désignation: MGMT (MGMT Produits)

Synonymes: anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt

Sujet:

Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Aliases: 6 O methylguanine DNA methyltransferase antibody, 6-O-methylguanine-DNA methyltransferase antibody, Agat antibody, AGT antibody, AI267024 antibody, EC 2.1.1.63 antibody, Methylated DNA protein cysteine methyltransferase antibody, Methylated-DNA--protein-cysteine methyltransferase antibody, Methylguanine DNA methyltransferase antibody, MGC107020 antibody, MGMT antibody, MGMT_HUMAN antibody, O 6 methylguanine DNA alkyltransferase antibody, O 6 methylguanine DNA methyltransferase antibody, O-6-methylguanine-DNA methyltransferase antibody, O-6-methylguanine-DNA-alkyltransferase antibody

UniProt: P16455

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus