IRF9 anticorps (AA 101-200) (Alexa Fluor 350)
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- Antigène Voir toutes IRF9 Anticorps
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Épitope
- AA 101-200
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF9 est conjugé à/à la Alexa Fluor 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human IRF9
- Isotype
- IgG
- Top Product
- Discover our top product IRF9 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Autre désignation
- IRF9 (IRF9 Produits)
- Synonymes
- anticorps IRF-9, anticorps ISGF3, anticorps ISGF3G, anticorps p48, anticorps zgc:92097, anticorps Irf-9, anticorps Isgf3g, anticorps interferon regulatory factor 9, anticorps IRF9, anticorps irf9, anticorps Irf9
- Sujet
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Synonyms: p48, IRF-9, ISGF3, ISGF3G, Interferon regulatory factor 9, IFN-alpha-responsive transcription factor subunit, ISGF3 p48 subunit, Interferon-stimulated gene factor 3 gamma, ISGF-3 gamma, Transcriptional regulator ISGF3 subunit gamma, IRF9
Background: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- ID gène
- 10379
- UniProt
- Q00978
- Pathways
- Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C
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