C5 anticorps
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- Antigène Voir toutes C5 Anticorps
- C5 (Complement Component 5 (C5))
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp C5 est non-conjugé
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Application
- Western Blotting (WB)
- Stérilité
- 0.2 μm filtered
- Top Product
- Discover our top product C5 Anticorps primaire
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- Indications d'application
- For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
- Restrictions
- For Research Use only
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- Buffer
- PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- Date de péremption
- 12 months
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- Antigène
- C5 (Complement Component 5 (C5))
- Abstract
- C5 Produits
- Synonymes
- anticorps C5, anticorps LOC565774, anticorps C5a, anticorps C5b, anticorps CPAMD4, anticorps Hc, anticorps RGD1561905, anticorps He, anticorps complement C5, anticorps complement component 5, anticorps hemolytic complement, anticorps C5, anticorps c5, anticorps Hc
- Sujet
- C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5a induces smooth muscle contraction, increases vascular permeability, causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Studies indicate the modulation of the acute-phase response in liver and an overall immune response by inducing synthesis of cytokines such as TNF-alpha, IL-1beta, IL-6 and IL-8. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.
- Pathways
- Système du Complément, Carbohydrate Homeostasis
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